Shared Research Facilities and Equipment

Many facilities across North Carolina support life science research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing please reach out to Susan Lankford.

 

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Region
Category
Facility Institution
Triangle
Durham
The Share Resource serves Duke and non-Duke researchers with Illumina (Hiseq 2000/2500 and MiSeq), Ion Torrent (PGM and Proton), and PacBio sequencing.
More information/services:

Roche 454, Illumina, SOLiD

  • Genetics & Genomics
Oliver Fedrigo
sequencing@duke.edu
(919) 684-3359
North Carolina State University
Triangle
Raleigh
The GSL provides Next Generation DNA sequencing, Sanger sequencing, genotyping and other support services to NC State faculty and the greater scientific research community.
More information/services:

High-throughput sequencing using lllumina and LifeTech platforms, DNA sequencing (Sanger) and genotyping. Automated pipelines for nucleic extraction from tissues and high-throughput processing of samples using robotic liquid handling.

  • Genetics & Genomics
David Andrew Baltzegar, Ph.D.
dabaltze@ncsu.edu
(919) 513-0738
East Carolina University
East
Greenville
The Genomics Core Facility provides DNA sequencing services for East Carolina University. The facility includes an Applied Biosystems 3130 Genetic Analyzer, Agilent 2100 Bioanalyzer, thermal cyclers, and Nanodrop 2000.
More information/services:

DNA and RNA quality analysis; nucleic acid sample preparation; DNA amplification; DNA sequencing; next-gen sequencing using the Ion Proton

  • Genetics & Genomics
Denise Mayer
mayerd@ecu.edu
(252) 328-2607
Triangle
Raleigh
BTEC houses 63,000 GSF of fermentation, cell culture, recovery, purification, and analytical lab space for training NC State students and industry professionals in bioprocessing. BTEC also offers its space and expertise for protein production and purification, process/technology development, and analytical testing/development, serving both industry and other academic labs. Pre-clinical processing for non-human use only, Good Large-scale Safety Practice only
More information/services:

pre-clinical process development, analytical testing, analytical test development, cGMP training, fermentation, BL-2 laboratory, cell culture, centrifugation, homogenization, chromatography, ultrafiltration, diafiltration, filtration, clean utilities

  • Bioprocessing
  • Cell/Tissue Culture & Flow Cytometry
  • Other -omics & Analytical
Gary Gilleskie, Ph.D.
glgilles@ncsu.edu
(919) 515-0176
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The UNC HTPSA Facility (part of the UNC Center for Structural Biology) provides researchers with high quality services for peptide synthesis, purification, and characterization of synthetic peptides and preparation of custom designed peptide arrays. We specialize in synthesis of multiply modified peptides containing PTMs, unnatural amino acids, and fluorescent tags.
More information/services:

PTI Symphony Multiple & PS-3 Peptide Synthesizer, Waters 2545 preparative HPLC system, Waters 1525 semi-prep HPLC system, Waters Alliance HPLC system, Mettler Toledo XP26 DeltaRange Microbalance, GeneMachines OmniGrid 100 Microarray Printer

  • Bioprocessing
  • Cell/Tissue Culture & Flow Cytometry
  • Crystallography, X-ray Diffraction, NMR, & EPR
Krzysztof Krajewski
kka@med.unc.edu
(919) 843-3935
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The mission of the Histology Research Core Facility is to provide high-quality, cost-effective and timely histological results to researchers in the UNC system and abroad. This includes performance of existing, and development of new methodology for histological processing, sectioning and staining of both plant and animal specimens and all immunohistochemistry procedures. Other services provided: nissl, x-gal, beta gal, sectioning, staining, counterstain, prussian blue, cresyl violet, sudan iv
More information/services:

histology, paraffin, frozen, microtome, cryostat, cryosection, immunofluorescence, immunohistochemistry, hematoxylin, eosin, H+E, masson's trichrome, oil red o, sirius red, picrosirius red, alcian blue, PAS, von kossa, DAB, fluorescence

  • Pathology/Histology
J. Ashley Ezzell
jezzell@email.unc.edu
(919) 966-1202
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The Hooker Imaging Core (HIC) is an open core providing standard and advanced light microscopy and image processing resources, including live cell/tissue, confocal and super resolution. Assistance is provided to enable users to acquire images from samples they have prepared. The HIC’s flagship confocal the Zeiss 880 has been upgraded with the Airyscan sensor to give users the extra resolution and sensitivity for those challenging samples. The HIC also has a newly installed upright Zeiss 800, to go along with a Fluoview 1000 and Zeiss 510 confocal. In addition to confocals the HIC has systems for long-term live cell imaging (VivaView), high content image screening (GE IN Cell Analyzer 2200) and wide field systems for color and fluorescence imaging. Training and other assistance will be provided by the core co-directors. The Faculty Advisor is Dr. Jim Bear.
More information/services:

Microscopy; microscope; imaging; light; image; processing; laser scanning; confocal; live cell; tissue; colocalization; fluorescence; FRAP; FRET; photoactivation; 3D; volume render; deconvolution; time lapse; montage; stereo; high-content screening

  • Imaging & Microdissection
Robert Currin
robert_currin@med.unc.edu
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
This state-of-the-art laboratory is designed to perturb, measure, and analyze human movement, primarily gait. The centerpieces of the lab are a 3D motion capture system, and dual-belt instrumented treadmill.
More information/services:

kinematic/kinetic/electromyographic monitoring, visual and proprioceptive feedback/perturbations

  • Human Performance, Nutrition, & Physiology
Michael Lewek, PT, PhD
mlewek@med.unc.edu
(919) 966-4041
Joint School of Nanoscience and Nanoengineering
Piedmont Triad
Greensboro
State-of-the-art suite of charged particle, scanning probe and optical microscopes, including Helium Ion Microscope, Crossbeam SEM/FIB with EDX, TEM, VP-SEM (Environmental) with EDX, FE-SEM, Atomic Force Microscope, Confocal and Hyperspectral/Dark-field Microscopes.
  • Nanotechnology
  • Diagnostic Microbiology
  • Imaging & Microdissection
Shyam Aravamudhan
jsnntools@ncat.uncg.edu
(336) 285-2856
Joint School of Nanoscience and Nanoengineering
Piedmont Triad
Greensboro
Suite of spectroscopic and chromatographic characterization instruments including X-ray Photoelectron Spectrometer (XPS), 400 and 700 MHz NMR, GC Ion Trap Mass Spectrometer, GC/LC Triple Quad Mass Spectrometer, LC/MS Ion Trap Mass Spectrometer, HPLC Liquid Chromatography System, X-Ray Diffractometer, Confocal Raman Confocal Microscope, UV-Vis Spectrophotometer, FTIR Spectrometer w/ATR, ICP-OES Axial Spectrometer, ICP Mass Spectrometer, Fluorescence Spectrophotometer, Zetasizer and Nanoparticle Tracking and Goniometer/Tensiometer.
  • Nanotechnology
  • Other -omics & Analytical
  • Crystallography, X-ray Diffraction, NMR, & EPR
Shyam Aravamudhan
jsnntools@ncat.uncg.edu
(336) 285-2856