Shared Research Facilities and Equipment
Many facilities across North Carolina support life sciences research.
The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.
Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.
NCBiotech has funded equipment in many core facilities in the state.
The Center's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing please fill this form.
Suite of spectroscopic and chromatographic characterization instruments including X-ray Photoelectron Spectrometer (XPS), 400 and 700 MHz NMR, GC Ion Trap Mass Spectrometer, GC/LC Triple Quad Mass Spectrometer, LC/MS Ion Trap Mass Spectrometer, HPLC Liquid Chromatography System, X-Ray Diffractometer, Confocal Raman Confocal Microscope, UV-Vis Spectrophotometer, FTIR Spectrometer w/ATR, ICP-OES Axial Spectrometer, ICP Mass Spectrometer, Fluorescence Spectrophotometer, Zetasizer and Nanoparticle Tracking and Goniometer/Tensiometer.
- Nanotechnology
- Other -omics & Analytical
- Crystallography, X-ray Diffraction, NMR, & EPR
The computational Modeling Core includes Cray XC-30 Supercomputer System (nano.ncat.edu) with CPU compute blades memory totaling 640 cores and GPU compute blades memory totaling 240 cores, HP 24-core Linux workstations, HP 32-core workstation, Visualization lab with 3D stereo-vision display system and the Mechdyne visualization suite and multiple Dell quad core computers. Software packages include Accelrys, Material Studio, ANSYS, GROMACS, Lammps, MATLAB. Training also available on I-Tasser, NAMD, VMD, Rasmol, QT/XMgrace, Material Studio, ANSYS, GROMACS, Lammps, MATLAB, SYBYL-X and Autodock.
- Biostatistics, Bioinformatics, & HPC
- Nanotechnology
Class 100/1000 micro and nanofabrication facility for top-down as well as bottom-up synthesis including for micro and nanoelectronics, MEMS, biofabrication, and microfluidics.
- Nanotechnology
- Design Services & Machining
JSNN Soft Matter & Nanobiology Core includes Biocleanroom, BSL2 and BSL3 Cell/Tissue Culture labs, Siemens Magnetom Trio MRI 3T, Spinning Disc Confocal Microscope with Live Cell Stage, Variable Pressure SEM with Deben cold stage, Fluorescence and Assay Systems, FACSAria III Flow Cytometer, Spectrophotometer, Microplate Sample Processor. Visio Trio Cell Profiling System, Agilent 2100 Bioanalyzer Horiba SPRi-Lab+ and Sequencing/Genomics instruments - MiSeq DNA Sequencer, Fast PCR System, Thermal Cycler and Gel Electrophoresis System.
- Nanotechnology
- Cell/Tissue Culture & Flow Cytometry
- Pharmaceutical & Drug Discovery
- Imaging & Microdissection
- Other -omics & Analytical
- Genetics & Genomics
- Diagnostic Microbiology
This is a user-operated facility that allows investigators to micro-dissect from tissue samples specific subsets of cells or sub-cellular structures, which usually are subjected to further protein or nucleic acid analyses. Users are required to undergo training.
Microdissection, LCM, User-operated
- Imaging & Microdissection
The Light Microscopy Core Facility (LMCF) offers a wide range of confocal and fluorescence microscopes and image analysis resources. We aim to offer affordable and efficient access to standard and advanced imaging instrumentation.
Light microscopy, fluorescence imaging, confocal, multiphoton, live cell imaging, image analysis
- Imaging & Microdissection
The Macromolecular Crystallography (MX) core, part of the UNC Center for Structural Biology, offers services in growing diffraction-quality protein crystals, including screening of crystal-producing experimental conditions and scaling up those conditions; as well as screening crystals for diffraction quality then collecting full datasets of diffraction images. We can also help determine your crystal structures, analyze them, and help you publish.
macromolecular crystallography, crystal growth, x-ray diffraction, synchrotron access
- Crystallography, X-ray Diffraction, NMR, & EPR
The Mac-In-Fac (part of the UNC Center for Structural Biology) provides instrumentation and resources for characterization of macromolecules and their interactions using isothermal and differential scanning microcalorimeters (ITC and DSC), surface plasmon resonance (SPR)-based biosensors, analytical ultracentrifuges, circular dichroism (CD) spectrometers, spectrofluorometer, fluorescence plate reader, and static and dynamic light scattering instruments.
Biomolecular Interactions, light scattering, SPR-based biosensor, Proteon XPR36, Biacore 3000, analytical ultracentrifugation,Auto-ITC200,DSC, microcalorimeters, fluorescence plate reader, circular dichroism, fluorimeter, molecular weight determination
- Bioprocessing
- Cell/Tissue Culture & Flow Cytometry
The Marine Conservation Molecular Facility (MCMF) is a shared use molecular lab for genetic analysis of marine organisms. The MCMF offers 8 bench spaces, 12 thermal cyclers, 2 real-time thermal cyclers, a pipetting robot, and an ABI Sequencer.
DNA sequencing, microsatellite analysis, SNP detection
- Genetics & Genomics
The Marine Magnetic Resonance Facility houses a 4.7 T 40 cm bore horizontal magnet. The flexibility of the instrument allows scientists to study questions ranging from how sea food spoils, to how toxins, drugs or even environmental stressors affect the physiology and biochemistry of marine animals.
NMR based metabolomics
- Other -omics & Analytical