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Shared Research Facilities and Equipment

Many facilities across North Carolina support life science research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing please reach out to Susan Lankford.

 

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Region
Category
Facility Institution
JSNN Computational Modeling Core
Joint School of Nanoscience and Nanoengineering
Piedmont Triad
Greensboro
The computational Modeling Core includes Cray XC-30 Supercomputer System (nano.ncat.edu) with CPU compute blades memory totaling 640 cores and GPU compute blades memory totaling 240 cores, HP 24-core Linux workstations, HP 32-core workstation, Visualization lab with 3D stereo-vision display system and the Mechdyne visualization suite and multiple Dell quad core computers. Software packages include Accelrys, Material Studio, ANSYS, GROMACS, Lammps, MATLAB. Training also available on I-Tasser, NAMD, VMD, Rasmol, QT/XMgrace, Material Studio, ANSYS, GROMACS, Lammps, MATLAB, SYBYL-X and Autodock.
  • Biostatistics, Bioinformatics, & HPC
  • Nanotechnology
Kristen Reinhardt
jsnntools@ncat.uncg.edu
(336) 285-2881
http://jsnn.ncat.uncg.edu/industry/research-tools-labs/
JSNN Micro and Nanofabrication Core
Joint School of Nanoscience and Nanoengineering
Piedmont Triad
Greensboro
Class 100/1000 micro and nanofabrication facility for top-down as well as bottom-up synthesis including for micro and nanoelectronics, MEMS, biofabrication, and microfluidics.
  • Nanotechnology
  • Design Services & Machining
Shyam Aravamudhan
jsnntools@ncat.uncg.edu
(336) 285-2856
http://jsnn.ncat.uncg.edu/industry/research-tools-labs/
JSNN Soft Matter & Nanobiology Core
Joint School of Nanoscience and Nanoengineering
Piedmont Triad
Greensboro
JSNN Soft Matter & Nanobiology Core includes Biocleanroom, BSL2 and BSL3 Cell/Tissue Culture labs, Siemens Magnetom Trio MRI 3T, Spinning Disc Confocal Microscope with Live Cell Stage, Variable Pressure SEM with Deben cold stage, Fluorescence and Assay Systems, FACSAria III Flow Cytometer, Spectrophotometer, Microplate Sample Processor. Visio Trio Cell Profiling System, Agilent 2100 Bioanalyzer Horiba SPRi-Lab+ and Sequencing/Genomics instruments - MiSeq DNA Sequencer, Fast PCR System, Thermal Cycler and Gel Electrophoresis System.
  • Nanotechnology
  • Cell/Tissue Culture & Flow Cytometry
  • Pharmaceutical & Drug Discovery
  • Imaging & Microdissection
  • Other -omics & Analytical
  • Genetics & Genomics
  • Diagnostic Microbiology
Shyam Aravamudhan
jsnntools@ncat.uncg.edu
(336) 285-2856
http://jsnn.ncat.uncg.edu/industry/research-tools-labs/
LCM Core Facility
University of North Carolina at Charlotte
Greater Charlotte
Charlotte
This is a user-operated facility that allows investigators to micro-dissect from tissue samples specific subsets of cells or sub-cellular structures, which usually are subjected to further protein or nucleic acid analyses. Users are required to undergo training.
More information/services:

Microdissection, LCM, User-operated

  • Imaging & Microdissection
Didier Dreau, Ph.D.
ddreau@uncc.edu
(704) 687-8314
Light Microscopy Core Facility
Duke University
Triangle
Durham
The Light Microscopy Core Facility (LMCF) offers a wide range of confocal and fluorescence microscopes and image analysis resources. We aim to offer affordable and efficient access to standard and advanced imaging instrumentation.
More information/services:

Light microscopy, fluorescence imaging, confocal, multiphoton, live cell imaging, image analysis

  • Imaging & Microdissection
Lisa Cameron
lisa.cameron@duke.edu
(919) 613-8216
http://microscopy.duke.edu/
Macromolecular Crystallography Core
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The Macromolecular Crystallography (MX) core, part of the UNC Center for Structural Biology, offers services in growing diffraction-quality protein crystals, including screening of crystal-producing experimental conditions and scaling up those conditions; as well as screening crystals for diffraction quality then collecting full datasets of diffraction images. We can also help determine your crystal structures, analyze them, and help you publish.
More information/services:

macromolecular crystallography, crystal growth, x-ray diffraction, synchrotron access

  • Crystallography, X-ray Diffraction, NMR, & EPR
Nathan Nicely
nathan.nicely@unc.edu
(919) 843-7174
http://www.med.unc.edu/csb/mx
Macromolecular Interactions Facility
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The Mac-In-Fac (part of the UNC Center for Structural Biology) provides instrumentation and resources for characterization of macromolecules and their interactions using isothermal and differential scanning microcalorimeters (ITC and DSC), surface plasmon resonance (SPR)-based biosensors, analytical ultracentrifuges, circular dichroism (CD) spectrometers, spectrofluorometer, fluorescence plate reader, and static and dynamic light scattering instruments.
More information/services:

Biomolecular Interactions, light scattering, SPR-based biosensor, Proteon XPR36, Biacore 3000, analytical ultracentrifugation,Auto-ITC200,DSC, microcalorimeters, fluorescence plate reader, circular dichroism, fluorimeter, molecular weight determination

  • Bioprocessing
  • Cell/Tissue Culture & Flow Cytometry
Ashutosh Tripathy
ashutosh_tripathy@med.unc.edu
(919) 962-4399
http://www.med.unc.edu/csb/macinfac
Marine Conservation Molecular Facility
Duke University
East
Beaufort
The Marine Conservation Molecular Facility (MCMF) is a shared use molecular lab for genetic analysis of marine organisms. The MCMF offers 8 bench spaces, 12 thermal cyclers, 2 real-time thermal cyclers, a pipetting robot, and an ABI Sequencer.
More information/services:

DNA sequencing, microsatellite analysis, SNP detection

  • Genetics & Genomics
Tom Schultz
Tom.Schultz@duke.edu
(252) 504-7641
https://nicholas.duke.edu/marinelab/about/facilities/marine-conservation-molecu…
Marine Magnetic Resonance Facility
North Carolina State University
East
Morehead City
The Marine Magnetic Resonance Facility houses a 4.7 T 40 cm bore horizontal magnet. The flexibility of the instrument allows scientists to study questions ranging from how sea food spoils, to how toxins, drugs or even environmental stressors affect the physiology and biochemistry of marine animals.
More information/services:

NMR based metabolomics

  • Other -omics & Analytical
Michael K. Stoskopf
michael_stoskopf@ncsu.edu
(252) 222-6370
http://cmast.ncsu.edu/programs-cmast/magnet/
Metabolic Molecular Phenotyping Core Facility
North Carolina Research Campus
Greater Charlotte
Kannapolis
The overall goal of the Choline & Metabolites Lab Facility is to provide cutting edge nutritional biochemical analysis of choline and metabolites in human, plant and mouse populations. To request choline & metabolites services, please complete our online service request form. [http://norc.sph.unc.edu/core_c/request_form.php]
More information/services:

Betaine, choline & metabolites, dimethylglycine, fatty acids, folate, homocysteine, methionine, phospholipid fatty acids, plasma, taurine, trimethylamine n-oxide (TMAO), trimethylamine (TMA), s-adenosylmethionine, sarcosine

  • Human Performance, Nutrition, & Physiology
  • Other -omics & Analytical
Sunil Hwang
sunil_hwang@unc.edu
(704) 250-5041
http://sph.unc.edu/norc/metabolic/