Shared Research Facilities and Equipment

Many facilities across North Carolina support life sciences research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing please fill this form.

 

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Region
Category
Facility Institution
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
More information/services:

nucleic acid extraction, repository services, bio-specimen processing

  • Bioprocessing
  • Biorepository
Patricia Basta
patricia_basta@unc.edu
919-843-3860
University of North Carolina at Pembroke
Southeast
Pembroke

Fermentation: bench to pilot scale We will provide affordable, practical hands-on training on bioreactor set-up, operation and harvest. Also, we will grow biomass (non-cGMP) for customers.

More information/services:

fermentation technology; microbial liquid culture

  • Bioprocessing
Len Holmes
len.holmes@uncp.edu
(910) 521-6650
University of North Carolina at Chapel Hill
Triangle
Chapel Hill

The BRIC Small Animal Imaging facility provides imaging of small species, including mice, rats, etc., as well as in vitro specimens. On-site modalities include MRI, optical, CT, PET, SPECT and ultrasound. With expertise in study design, animal models, image acquisition and image analysis, the Small Animal Imaging facility helps investigators from grant application to publication. Services are available to investigators from all academic and industry labs.

More information/services:

imaging, small animal imaging, MRI, PET, microPET, SPECT, nuclear medicine, CT, microCT, ultrasound, US, optical, fluorescence, luminescence, autoradiography, DXA, DEXA, image analysis

  • Imaging & Microdissection
Hong Yuan, PhD
bricsai@unc.edu
(919) 843-3813
Triangle
Durham

The High-Throughput Screening (HTS) and Drug Discovery Core Facility satisfies the demand for drug discovery and screening needs. With our flexible screening schedule and shared resources, we can perform the entire screen for you or share our equipment for your screening use. Our facility maintains a large chemical library and houses multiple liquid handling and assay detection instrumentation on site. Our HTS capabilities extend from 6- to 384-well plates and include almost all detection formats for both biochemical and cellular assays, including absorbance, fluorescence, luminescence, fluorescence polarization, time-resolved fluorescence, FLIPR, high-content imaging, and live-cell detection.

More information/services:

Drug Discovery; High Throughput Screening (HTS); Compound Libraries; Chemical Libraries; Assay Development; Assays; Shared Resources; Assay Detection; Small Molecules; Drug Like Molecules; Target-Based

  • Pharmaceutical & Drug Discovery
John E. Scott, PhD
jscott@nccu.edu
(919) 530-7569
North Carolina Central University
Triangle
Durham

This core facility offers high-resolution imaging of biological samples, including fluorescence microscopy, confocal high content imaging, and Widefield. It also features live cell imaging in high throughput format and calcium influx-efflux measurement using FLIPER.

  • Imaging & Microdissection
kding@nccu.edu
North Carolina Central University
Triangle
Durham

This core facility offers large-scale expression and purification services for biopharmaceutical research and performs investigations of protein stability/aggregation using several advanced methods.

More information/services:

30-liter bioreactor, E. coli, bacular virus, and mammalian cell expression systems, differential scanning calorimetry, self-interaction chromatography, dynamic light scattering, circular dichroism

  • Pharmaceutical & Drug Discovery
  • Other -omics & Analytical
kding@nccu.edu
North Carolina Central University
Triangle
Durham

This facility features atomic force microscopy and biosensor development. It also offers laser scanning confocal microscope, 500 MHz NMR, flow cytometry, TOF-MS, and HTS capillary electophoresis.

  • Cell/Tissue Culture & Flow Cytometry
  • Imaging & Microdissection
  • Other -omics & Analytical
kding@nccu.edu
(919) 530-6884
East Carolina University
East
Greenville

This is a user-operated facility housing the following instrumentation to meet specialized microscopy, flow cytometer and protein quantification applications: -Zeiss PALM Laser Capture Microdissection scope -Zeiss LSM 700 Confocal with on stage incubation system -Becton Dickinson LSR II analytical flow cytometer (4laser, 14 channel detection)'- Protein Simple WES- an automated capillary/western assay system

More information/services:

Imaging, microdissection, flow cytometry, protein analysis

  • Cell/Tissue Culture & Flow Cytometry
  • Imaging & Microdissection
Cindy Kukoly
kukolyc@ecu.edu
(252) 744-2962
North Carolina State University
Triangle
Raleigh

The CALS Center for Electron Microscopy provides scanning and transmission electron microscopy services including associated tissue preparation for the biological sciences. Digital imaging services are also available.

More information/services:

Transmission electron microscopy, Scanning electron microscopy, TEM, SEM, Ultramicrotomy, Critical point drying, Sputter coating, Biological samples, Digital Imaging

  • Imaging & Microdissection
Valerie Knowlton Lapham
valerie_knowlton@ncsu.edu
(919) 515-2664
Triangle
Buies Creek

The Pharmaceutical Education & Research Center (PERC) at Campbell University offers a wide variety of analytical, formulation, R&D, and training services to pharmaceutical and biotechnology industries, compounding pharmacies, and academic institutions.

More information/services:

Pre-Clinical Trial Materials, Analytical Testing, Formulation Development, Stability Testing, Analytical Method Development

  • Crystallography, X-ray Diffraction, NMR, & EPR
  • Pharmaceutical & Drug Discovery
  • Other -omics & Analytical
Mali R. Gupta, Ph.D.
guptam@campbell.edu
(910) 893-1694
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