Shared Research Facilities and Equipment

Many facilities across North Carolina support life sciences research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing please reach out to Susan Lankford.

Biotechnology Research and Training Center (BRTC)

University of North Carolina at Pembroke

Southeast

Pembroke

Fermentation: bench to pilot scale We will provide affordable, practical hands-on training on bioreactor set-up, operation and harvest. Also, we will grow biomass (non-cGMP) for customers.

fermentation technology; microbial liquid culture

Bioprocessing

Len Holmes

len.holmes@uncp.edu

(910) 521-6650

http://www.uncp.edu/biotech

BRIC Small Animal Imaging Facility

University of North Carolina at Chapel Hill

Triangle

Chapel Hill

The BRIC Small Animal Imaging facility provides imaging of small species, including mice, rats, etc., as well as in vitro specimens. On-site modalities include MRI, optical, CT, PET, SPECT and ultrasound. With expertise in study design, animal models, image acquisition and image analysis, the Small Animal Imaging facility helps investigators from grant application to publication. Services are available to investigators from all academic and industry labs.

imaging, small animal imaging, MRI, PET, microPET, SPECT, nuclear medicine, CT, microCT, ultrasound, US, optical, fluorescence, luminescence, autoradiography, DXA, DEXA, image analysis

Imaging & Microdissection

Hong Yuan, PhD

bricsai@unc.edu

(919) 843-3813

http://www.med.unc.edu/bric/small-animal-imaging

BRITE Drug Discovery Core

North Carolina Central University

Triangle

Durham

The drug discovery core facility is a state-of-the-art high throughput screening (HTS) facility with over 450,000 compound small molecule chemical libraries. It specializes in assay development, HTS, medicinal chemistry and chemo-informatics for drug discovery.

Assay development: cloning expression, protein production, High throughput screening: compound & database management, Medicinal chemistry: organic synthesis, SAR, parallel synthesis, nature product synthesis, Chemo-informatics: molecular modeling, QSAR

Pharmaceutical & Drug Discovery

kding@nccu.edu

(919) 530-7001

BRITE Imaging Core

North Carolina Central University

Triangle

Durham

This core facility offers high-resolution imaging of biological samples, including fluorescence microscopy, confocal high content imaging, and Widefield. It also features live cell imaging in high throughput format and calcium influx-efflux measurement using FLIPER.

Imaging & Microdissection

kding@nccu.edu

http://brite.nccu.edu/facility

BRITE Protein Expression and Purification Core

North Carolina Central University

Triangle

Durham

This core facility offers large-scale expression and purification services for biopharmaceutical research and performs investigations of protein stability/aggregation using several advanced methods.

30-liter bioreactor, E. coli, bacular virus, and mammalian cell expression systems, differential scanning calorimetry, self-interaction chromatography, dynamic light scattering, circular dichroism

Pharmaceutical & Drug Discovery
Other -omics & Analytical

kding@nccu.edu

http://brite.nccu.edu/facility

BRITE Technology Core

North Carolina Central University

Triangle

Durham

This facility features atomic force microscopy and biosensor development. It also offers laser scanning confocal microscope, 500 MHz NMR, flow cytometry, TOF-MS, and HTS capillary electophoresis.

Cell/Tissue Culture & Flow Cytometry
Imaging & Microdissection
Other -omics & Analytical

kding@nccu.edu

(919) 530-6884

BSOM Cellular Analysis/Imaging Core

East Carolina University

East

Greenville

This is a user-operated facility housing the following instrumentation to meet specialized microscopy, flow cytometer and protein quantification applications: -Zeiss PALM Laser Capture Microdissection scope -Zeiss LSM 700 Confocal with on stage incubation system -Becton Dickinson LSR II analytical flow cytometer (4laser, 14 channel detection)'- Protein Simple WES- an automated capillary/western assay system

Imaging, microdissection, flow cytometry, protein analysis

Cell/Tissue Culture & Flow Cytometry
Imaging & Microdissection

Cindy Kukoly

kukolyc@ecu.edu

(252) 744-2962

http://www.ecu.edu/cs-dhs/bsomresearchgradstudies/coreimagingcenter/

CALS Center for Electron Microscopy

North Carolina State University

Triangle

Raleigh

The CALS Center for Electron Microscopy provides scanning and transmission electron microscopy services including associated tissue preparation for the biological sciences. Digital imaging services are also available.

Transmission electron microscopy, Scanning electron microscopy, TEM, SEM, Ultramicrotomy, Critical point drying, Sputter coating, Biological samples, Digital Imaging

Imaging & Microdissection

Valerie Knowlton Lapham

valerie_knowlton@ncsu.edu

(919) 515-2664

https://harvest.cals.ncsu.edu/structural-biochemistry-resource/electron-microsc…

Campbell University Pharmaceutical Education and Research Center

Campbell University

Triangle

Buies Creek

The Pharmaceutical Education & Research Center (PERC) at Campbell University offers a wide variety of analytical, formulation, R&D, and training services to pharmaceutical and biotechnology industries, compounding pharmacies, and academic institutions.

Pre-Clinical Trial Materials, Analytical Testing, Formulation Development, Stability Testing, Analytical Method Development

Crystallography, X-ray Diffraction, NMR, & EPR
Pharmaceutical & Drug Discovery
Other -omics & Analytical

Mali R. Gupta, Ph.D.

guptam@campbell.edu

(910) 893-1694

http://www.campbell.edu/PERC

Campbell University Pharmaceutical Education and Research Center (PERC)

Campbell University

Triangle

Buies Creek

Pre-Clinical Trial Materials, Analytical Testing, Formulation Development, Stability Testing, Analytical Method Development

Crystallography, X-ray Diffraction, NMR, & EPR
Pharmaceutical & Drug Discovery
Other -omics & Analytical

Mali R. Gupta, Ph.D.

guptam@campbell.edu

(910) 893-1694

http://www.campbell.edu/PERC