Shared Research Facilities and Equipment

Many facilities across North Carolina support life sciences research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing please reach out to Susan Lankford.

METRIC

North Carolina State University

Triangle

Raleigh

METRIC is focused on advanced molecular characterization and is one of five NC State Shared Core Research Facilities administered by the Office of Research and Innovation. We offer technical expertise and state-of-the-art instrumentation encompassing magnetic resonance spectroscopy, mass spectrometry, and X-ray crystallography.

Mass Spectrometry, NMR Spectroscopy, X-ray Crystallography

Crystallography, X-ray Diffraction, NMR, & EPR
Other -omics & Analytical

Allison Stewart

akstewar@ncsu.edu

(919) 513-7910

https://research.ncsu.edu/metric/

MHI Animal Surgery Core Lab

University of North Carolina at Chapel Hill

Triangle

Chapel Hill

This MHI Core Laboratory provides a variety of established and experiment-specific small animal surgical/microsurgical models for a broad range of research applications, with the primary function of meeting investigator needs. The Core Faculty Director and staff have extensive experience with mouse, rat, and other animal models across many disciplines. The Core focuses on murine models which have become a predominant tool for many research labs. The Core Director will meet with PIs and/or staff and students to discuss model selection, development, and applications, as well as data acquisition and analysis. Power analyses for group size determination can be done from existing data sets of the PI or from validation data established by the Core. There are also self-service equipment offerings, which include ultrasound, microsurgical work station rental, non-invasive blood pressure monitoring, and intravital confocal microscopy.

animal surgery, non-invasive animal procedures

Model Systems

Brian C. Cooley

brian_cooley@med.unc.edu

(919) 962-4912

http://www.med.unc.edu/mhi/advsurgmodels

Microscopy Services Laboratory

University of North Carolina at Chapel Hill

Triangle

Chapel Hill

Our mission is to help YOU with YOUR research. Electron microscopy services include project consultation, sample preparation, imaging and training on transmission and scanning electron microscopes. Light microscopy services include project consultation and training on image acquisition. Confocal, light-sheet, widefield fluorescence, darkfield, and polarization microscopy available. Image analysis services including training on image analysis (3D and 2D analysis, colocalization, macros, etc.)

light microscopy, electron microscopy, confocal, live-cell imaging, transmitted electron microscopy, scanning electron microscopy, light-sheet microscopy

Imaging & Microdissection

Pablo Ariel

pablo_ariel@med.unc.edu

(919) 966-2413

http://www.med.unc.edu/microscopy

Molecular Core Lab

University of North Carolina at Greensboro

Piedmont Triad

Greensboro

The Molecular Core Lab houses an ABI 7500 realtime PCR system, Promega's Maxwell 16 MDX for small scale automated DNA/RNA extraction, Biorad's Transblot Turbo Transfer system for Western blotting, Bioanalyzer and Nanodrop for DNA/RNA quantification and quality testing.

DNA /RNA extraction, quantification & quality testing; qPCR; SNP Genotyping(using Taqman probes); Polyacrylamide Gel electrophoresis & Western blot;Cloning; Mammalian & insect cell culture assay; Site-directed mutagenesis & other mutational techniques

Bioprocessing
Biorepository
Cell/Tissue Culture & Flow Cytometry
Genetics & Genomics

Renuka Shivaji

r_shiva2@uncg.edu

(336) 256-8570

http://molecularcorelab.uncg.edu

Molecular Genetics Research Lab

North Carolina State University

West

Mills River

Molecular genetics analysis including genotyping of populations for molecular markers analysis, QTL analysis and marker-assisted selection. The real-time PCR can be used for gene expression analysis. All investigators working at Mountain Horticultural Crops Research and Extension Center (MHCREC) will have free access to use any of these equipment for their research. However, they will have to schedule their time in coordination with the technician from the tomato breeding program. Investigators from outside the MHCREC are also encouraged to use the research facility whenever necessary. All users are expected to contribute supplies, particularly QIAxcel cartridge, micro plates, grinding beads, and tubes.

Capillary electrophoresis, DNA extraction, Genotyping, Marker-assisted selection (MAS), Real-time PCR

Genetics & Genomics

Dilip Panthee, Ph.D

dilip_panthee@ncsu.edu

(828) 654-8590

NanoBio Launchpad

Gateway Research Park

Piedmont Triad

Greensboro

The NanoBio Launchpad is a unique co-working environment for start-ups and small businesses needing access to high tech laboratory space. This co-working environment is utilized to support “start-up” operations of newly formed nano-bio related entities and other small businesses. NanoBio Launchpad users are provided with desk space, telephone and internet access as well as lab bench space in a lab equipped with fume hood, chemical storage, and basic lab equipment. The lab location, adjacent to JSNN provides the added opportunity to access the specialty JSNN equipment, instruments and tools through the NanoManufacturing Innovation Consortium (NIC).

NanoBiology, Lab rental space

Nanotechnology

John Merrill

johnm@gatewayurp.com

(336) 375-9232

http://www.gatewayurp.com/

NCSU Flow Cytometry and Cell Sorting Facility

North Carolina State University

Triangle

Raleigh

The laboratory provides instrumentation and assistance for multi-parameter flow cytometric analysis and sorting. It is available for use to all NCSU researchers and to those outside the NCSU community and operates as a by appointment, fee for service lab.

Cell Sorting, Flow Cytometry, CytoFLEX, BD LSRII, MoFlo-XDP, AutoMACS, Seahorse XF, LunaII cell counter, Flourochromes, Lasers, BSL2, BSL2+ cell sorting

Cell/Tissue Culture & Flow Cytometry

Javid Mohammed

jpmohamm@ncsu.edu

(919) 513-6443

https://cvm.ncsu.edu/research/labs/flow-cytometry-and-cell-sorting-laboratory/

NMR Facility

University of North Carolina at Greensboro

Piedmont Triad

Greensboro

The NMR Facility houses a JEOL 400MHz spectrometer with a 24 position sample changer system and a JEOL 500MHz spectrometer. Both normal geometry and capillary NMR probes are available for small molecule elucidation and high-throughput screening.

NMR structural analysis, NMR screening

Crystallography, X-ray Diffraction, NMR, & EPR

Franklin Moy, Ph.D.

fjmoy@uncg.edu

(336) 334-3006

http://www.uncg.edu/che/facilities/nmr/nmr.html

North Carolina State University Mass Spectrometry Facility

North Carolina State University

Triangle

Raleigh

The North Carolina State University Mass Spectrometry Facility (NCSU MSF) offers a variety of mass spectrometers providing analysis through an array of methods for sample introduction, ionization and mass measurement. Our mass spectrometers include the following: Thermo Fisher Scientific LTQ Orbitrap XL, Agilent Technologies 6210 LC-TOF, Agilent Technologies 5975 GC/MS, Thermo Fisher Scientific TSQ Quantum Discovery MAX Triple Quadrupole MS, Agilent Technologies GCD and AB Sciex 5800 MALDI-TOF/TOF MS.

Mass spectrometry, accurate mass analysis, MS/MS, gas chromatography, MALDI, liquid chromatography, proteomics, small molecule analysis, quantification

Other -omics & Analytical

Taufika Islam Williams, PhD

Taufika_Williams@ncsu.edu

(919) 513-7791

http://www.ncsu.edu/chemistry/msf/

Plastic and Reconstructive Surgery Hyperthermia Lab

Wake Forest University

Piedmont Triad

Winston-Salem

Animal imaging and hyperthermia treatment analysis consisting of a Quantum Design, Inc., DM100 series magnetic hyperthermia instrument and K-Laser Cube infrared laser system.

hyperthermia and thermal imaging

Imaging & Microdissection
Nanotechnology
Other -omics & Analytical

Nicole Levi-Polyachenko

nlevi@wakehealth.edu

(336) 713-8052