Shared Research Facilities and Equipment

Many facilities across North Carolina support life sciences research.

The listing covers core laboratory facilities at universities and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

NCBiotech's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing, please fill out this form.

 

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Region
Category
Facility Institution
North Carolina State University
Triangle
Raleigh

The laboratory provides instrumentation, training, and assistance for multi-parameter flow cytometric analysis and sorting. It is available for use to all NCSU researchers and to those outside the NCSU community. The facility operates as a by appointment, fee for service lab.

More information/services:

Flow Cytometry, Cell Sorting, FACS, CytoFLEX, LSRII, MoFlo-XDP, Seahorse XF, Luna-II Cell Counter, Nanostring, RNA Quantification, Fluorophores, BSL2, BLS2+ Cell Sorting

  • Cell/Tissue Culture & Flow Cytometry
Dr. David Rose
(919) 513-6443
University of North Carolina at Greensboro
Piedmont Triad
Greensboro

The NMR Facility houses a JEOL 400MHz spectrometer with a 24 position sample changer system and a JEOL 500MHz spectrometer. Both normal geometry and capillary NMR probes are available for small molecule elucidation and high-throughput screening.

More information/services:

NMR structural analysis, NMR screening

  • Crystallography, X-ray Diffraction, NMR, & EPR
Franklin Moy, Ph.D.
(336) 334-3006
Triangle
Durham

The OneDukebio Integrated biospecimen Network (ODIN) is a shared resource created in 2021 that provides full-service biospecimen allocation and management. This state-of-the-art centralized biorepository follows biobanking best practices and operates under Good Clinical Laboratory Practice (GCLP) guidelines to ensure the integrity of specimens.

More information/services:

storage of blood, body fluids, and tissue, room temperature, 4°C, -80°C, -150°C liquid nitrogen

  • Biorepository
David Layfield
(919) 668-0232
University of North Carolina at Chapel Hill
Triangle
Chapel Hill

The Pathology Services Core is a core facility in the UNC School of Medicine administered by the Lineberger Comprehensive Cancer Center and the Department of Pathology and Laboratory Medicine. We offer access to sophisticated digital pathology platforms and study design support to all UNC investigators to enhance translational research. Services are also open to users from other academic institutions and industry.

More information/services:

Processing, embedding, FFPE sectioning, Frozen sectioning, Tissue Micro Array (TMA) design and construction, H&E, special stains, IHC, multiplex IF, in situ hybridization (ISH and FISH), digital slide scanning and image storage, quantitative analysis of digital microscopy images, Pathologist consultation, Spatial Biology, spatial phenotyping.

  • Pathology/Histology
Gabriela De la Cruz
919-758-6544
Plastic and Reconstructive Surgery Hyperthermia Lab
Wake Forest University
Piedmont Triad
Winston-Salem

Animal imaging and hyperthermia treatment analysis consisting of a Quantum Design, Inc., DM100 series magnetic hyperthermia instrument and K-Laser Cube infrared laser system.

More information/services:

hyperthermia and thermal imaging

  • Imaging & Microdissection
  • Nanotechnology
  • Other -omics & Analytical
Nicole Levi-Polyachenko
(336) 713-8052
University of North Carolina at Chapel Hill
Greater Charlotte
Kannapolis
More information/services:

Nutrigenomics, microbiome analysis, whole genome, exome, targeted gene sequencing, RNA-sequencing, microbiota characterization, DNA, RNA, bomb calorimetry, consulting

  • Genetics & Genomics
  • Human Performance, Nutrition, & Physiology
  • Other -omics & Analytical
Saroja Voruganti, PhD
(704) 250-5009
University of North Carolina at Chapel Hill
Triangle
Chapel Hill

The BRIC Small Animal Imaging facility provides imaging of small species, including mice, rats, etc., as well as in vitro specimens. On-site modalities include MRI, optical, CT, PET, SPECT and ultrasound. With expertise in study design, animal models, image acquisition and image analysis, the Small Animal Imaging facility helps investigators from grant application to publication. Services are available to investigators from all academic and industry labs.

More information/services:

imaging, small animal imaging, MRI, PET, microPET, SPECT, nuclear medicine, CT, microCT, ultrasound, US, optical, fluorescence, luminescence, autoradiography, DXA, DEXA, image analysis

  • Imaging & Microdissection
Hong Yuan, PhD
(919) 843-3813
Piedmont Triad
Winston-Salem

The Proteomics and Metabolomics Shared Resource provides broad mass spectrometry services to academic and industry investigators. The PMSR mission is to provide access to advanced mass spectrometry techniques for quantitation and identification of proteins, metabolites and other molecules of interest in biological and clinical samples. In addition to the fee-for-service, the Shared Resource offers options to accommodate various needs such as training and project-based collaborations. All services are scheduled and managed through iLab https://wfbmc.ilabsolutions.com/account/login).

More information/services:

proteomics (discovery and targeted analysis of proteins and posttranslational modifications including phosphorylation, acetylation, oxidation, etc)), metabolomics, lipidomics, pharmacokinetics

  • Other -omics & Analytical
Cristina M. Furdui
(336) 716-2697
University of North Carolina at Chapel Hill
Triangle
Chapel Hill

We provide consultations and collaborations on research studies requiring computational structural biology methods. The analyses available through the core (part of the UNC Center for Structural Biology) are not limited to the study of static structures, but also include molecular dynamics studies for analyzing the contribution of dynamic and collective motions to macromolecular functionality.

More information/services:

structure visualization, modeling and analysis, sequence analysis, Protein Data Bank (PDB) and Pymol Modeling

  • Biostatistics, Bioinformatics, & HPC
  • Crystallography, X-ray Diffraction, NMR, & EPR
  • Pharmaceutical & Drug Discovery
Venkata Reddy Chirasani
(919) 966-5044
Greater Charlotte
Charlotte

We are a histology oriented core lab that has the ability to perform a range of histological services. Mallory Korman, HTL (ASCP) has recently joined the team as the supervisor and primary contact for scientific help. Prior to this position, Mallory had managed the Research Histology Core laboratory at Stony Brook Medical Center in New York for five years and had maintained excellent standards quality, effectiveness and efficiency. These standards are our top priority here at Carolinas HealthCare System and we will be more than happy to help you obtain your histological goals. We offer scientific help to help clients prepare for their study in order to yield the most optimal histological results. We work with a large range of species which also includes human sample studies. We feel it’s important to first help the client to understand the best possible ways to prepare their samples depending on what assays they would like to have completed. This helps to ensure that the obtained results are as optimal as possible.

More information/services:

histological processing, paraffin embedding, sectioning tissue via microtome as well as cryostat, H&E staining, immunohistochemistry, immunofluorescence, bone decalcification, tissue microarray construction

  • Pathology/Histology
Mallory Korman
704-446-4632
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