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Shared Research Facilities and Equipment

Many facilities across North Carolina support life science research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal.
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Region
Category
Facility Institution
Molecular Core Lab
University of North Carolina at Greensboro
Piedmont Triad
Greensboro
The Molecular Core Lab houses an ABI 7500 realtime PCR system, Promega's Maxwell 16 MDX for small scale automated DNA/RNA extraction, Biorad's Transblot Turbo Transfer system for Western blotting, Bioanalyzer and Nanodrop for DNA/RNA quantification and quality testing.
More information/services:

DNA /RNA extraction, quantification & quality testing; qPCR; SNP Genotyping(using Taqman probes); Polyacrylamide Gel electrophoresis & Western blot;Cloning; Mammalian & insect cell culture assay; Site-directed mutagenesis & other mutational techniques

  • Bioprocessing
  • Biorepository
  • Cell/Tissue Culture & Flow Cytometry
  • Genetics & Genomics
Renuka Shivaji
r_shiva2@uncg.edu
(336) 256-8570
http://molecularcorelab.uncg.edu
Molecular Genetics Research Lab
North Carolina State University
West
Mills River
Molecular genetics analysis including genotyping of populations for molecular markers analysis, QTL analysis and marker-assisted selection. The real-time PCR can be used for gene expression analysis. All investigators working at Mountain Horticultural Crops Research and Extension Center (MHCREC) will have free access to use any of these equipment for their research. However, they will have to schedule their time in coordination with the technician from the tomato breeding program. Investigators from outside the MHCREC are also encouraged to use the research facility whenever necessary. All users are expected to contribute supplies, particularly QIAxcel cartridge, micro plates, grinding beads, and tubes.
More information/services:

Capillary electrophoresis, DNA extraction, Genotyping, Marker-assisted selection (MAS), Real-time PCR

  • Genetics & Genomics
Dilip Panthee, Ph.D
dilip_panthee@ncsu.edu
(828) 654-8590
NanoBio Launchpad
Gateway Research Park
Piedmont Triad
Greensboro
The NanoBio Launchpad is a unique co-working environment for start-ups and small businesses needing access to high tech laboratory space. This co-working environment is utilized to support “start-up” operations of newly formed nano-bio related entities and other small businesses. NanoBio Launchpad users are provided with desk space, telephone and internet access as well as lab bench space in a lab equipped with fume hood, chemical storage, and basic lab equipment. The lab location, adjacent to JSNN provides the added opportunity to access the specialty JSNN equipment, instruments and tools through the NanoManufacturing Innovation Consortium (NIC).
More information/services:

NanoBiology, Lab rental space

  • Nanotechnology
John Merrill
johnm@gatewayurp.com
(336) 375-9232
http://www.gatewayurp.com/
NCSU Flow Cytometry and Cell Sorting Facility
North Carolina State University
Triangle
Raleigh

The laboratory provides instrumentation and assistance for multi-parameter flow cytometric analysis and sorting. It is available for use to all NCSU researchers and to those outside the NCSU community and operates as a by appointment, fee for service lab.

More information/services:

Cell Sorting, Flow Cytometry, CytoFLEX, BD LSRII, MoFlo-XDP, AutoMACS, Seahorse XF, LunaII cell counter, Flourochromes, Lasers, BSL2, BSL2+ cell sorting

  • Cell/Tissue Culture & Flow Cytometry
Javid Mohammed
jpmohamm@ncsu.edu
(919) 513-6443
https://cvm.ncsu.edu/research/labs/flow-cytometry-and-cell-sorting-laboratory/
NMR Facility
University of North Carolina at Greensboro
Piedmont Triad
Greensboro
The NMR Facility houses a JEOL 400MHz spectrometer with a 24 position sample changer system and a JEOL 500MHz spectrometer. Both normal geometry and capillary NMR probes are available for small molecule elucidation and high-throughput screening.
More information/services:

NMR structural analysis, NMR screening

  • Crystallography, X-ray Diffraction, NMR, & EPR
Franklin Moy, Ph.D.
fjmoy@uncg.edu
(336) 334-3006
http://www.uncg.edu/che/facilities/nmr/nmr.html
North Carolina State University Mass Spectrometry Facility
North Carolina State University
Triangle
Raleigh
The North Carolina State University Mass Spectrometry Facility (NCSU MSF) offers a variety of mass spectrometers providing analysis through an array of methods for sample introduction, ionization and mass measurement. Our mass spectrometers include the following: Thermo Fisher Scientific LTQ Orbitrap XL, Agilent Technologies 6210 LC-TOF, Agilent Technologies 5975 GC/MS, Thermo Fisher Scientific TSQ Quantum Discovery MAX Triple Quadrupole MS, Agilent Technologies GCD and AB Sciex 5800 MALDI-TOF/TOF MS.
More information/services:

Mass spectrometry, accurate mass analysis, MS/MS, gas chromatography, MALDI, liquid chromatography, proteomics, small molecule analysis, quantification

  • Other -omics & Analytical
Taufika Islam Williams, PhD
Taufika_Williams@ncsu.edu
(919) 513-7791
http://www.ncsu.edu/chemistry/msf/
Plastic and Reconstructive Surgery Hyperthermia Lab
Wake Forest University
Piedmont Triad
Winston-Salem
Animal imaging and hyperthermia treatment analysis consisting of a Quantum Design, Inc., DM100 series magnetic hyperthermia instrument and K-Laser Cube infrared laser system.
More information/services:

hyperthermia and thermal imaging

  • Imaging & Microdissection
  • Nanotechnology
  • Other -omics & Analytical
Nicole Levi-Polyachenko
nlevi@wakehealth.edu
(336) 713-8052
Proteomics and Metabolomics Shared Resource - WFU
Wake Forest University
Piedmont Triad
Winston-Salem
The Proteomics and Metabolomics Shared Resource provides broad mass spectrometry services to academic and industry investigators. The PMSR mission is to provide access to advanced mass spectrometry techniques for quantitation and identification of proteins, metabolites and other molecules of interest in biological and clinical samples. In addition to the fee-for-service, the Shared Resource offers options to accommodate various needs such as training and project-based collaborations. All services are scheduled and managed through iLab https://wfbmc.ilabsolutions.com/account/login).
More information/services:

proteomics (discovery and targeted analysis of proteins and posttranslational modifications including phosphorylation, acetylation, oxidation, etc)), metabolomics, lipidomics, pharmacokinetics

  • Other -omics & Analytical
  • Other -omics & Analytical
Cristina M. Furdui
cfurdui@wakehealth.edu
(336) 716-2697
http://www.wakehealth.edu/Research/Comprehensive-Cancer-Center/PM/Proteomics-an…
Shared Materials Instrumentation Facility (SMIF)
Duke University
Triangle
Durham
SMIF provides researchers with access to advanced characterization and clean room fabrication capabilities. SMIF is available to all Duke University researchers and to external users from other universities, government labs, and industry. Small Angle X-Ray Scattering, Micro-CT X-Ray imaging
More information/services:

Electron Microscopy(SEM,TEM),Atomic Force Microscopy,Optical Spectroscopy(Raman,TIR,UV-Vis),XPS, X-ray Diffraction,E-Beam & Optical Lithography,Evaporation,Sputter & PECVD Deposition, RIE & Chemical Etching, Furnace Processing

  • Crystallography, X-ray Diffraction, NMR, & EPR
  • Imaging & Microdissection
  • Nanotechnology
Mark D. Walters, Ph.D.
mark.walters@duke.edu
(919) 660-5486
http://smif.pratt.duke.edu
Triad Mass Spectrometry Laboratory
University of North Carolina at Greensboro
Piedmont Triad
Greensboro
The TMS Laboratory provides mass spectrometry analysis and training to the UNC-Greensboro campus community and the surrounding Piedmont Triad. Our instrumentation can be tailored to small molecule, metabolomics, and/or protein/peptide analyses. Ionization Sources: ESI, APPI, APCI, MALDI, DESI Separation Instrumentation: Waters Aquity UPLC, Agilent 1100 HPLC Open to scientific researchers in the Piedmont Triad on a fee for service basis who are in need of mass spectrometry analysis. (Please see website http:triadmslab.uncg.edu)
More information/services:

MS instrumentation: Thermo Q Exactive Plus, Thermo LTQ Orbitrap XL, Thermo TSQ Quantum Access (triple quad), Waters Synapt G2 HDMS qTOF, Shimadzu GC-MS

  • Other -omics & Analytical
Daniel A. Todd, Ph.D.
Datodd3@uncg.edu
(336) 334-4768
http://triadmslab.uncg.edu