Shared Research Facilities and Equipment

The Protein Expression and Purification (PEP) core (part of the UNC Center for Structural Biology) specializes in the production of pure, functional proteins for structural, biophysical, and biochemical studies.

The Proteomics Core facility provides services for the analysis of proteins from tissues, cells or other biological samples. We are available to the UNC community, as well as external customers worldwide. We are committed to educating students and researchers in the field of proteomics and will work with you from initial experimental design through publication.

We offer an array of sample preparation and instrumentation services, as well as method development and in-depth consultation to help researchers optimize their experimental design. The facility is equipped with four state-of-the-art systems: Thermo QExactive HF, Thermo QExactive HF Biopharma, Thermo Fusion Lumos Tribrid and Thermo Exploris480. In addition to the mass spectrometers, we have one Thermo Ultimate3000, three Thermo Easy nLC 1200s and a 908 Devices ZipChip capillary electrophoresis device for up-front separation. We have an Agilent 1260 Infinity II HPLC for offline peptide fractionation. We offer several services including: protein identification, protein characterization, post-translational modification (PTM) profiling (for example: phosphoproteomics, acetylomics), large-scale proteomic profiling, intact mass analysis, and protein-protein interaction analyses. We can perform these services quantitatively using labeled (TMT10plex/16plex/18plex) or label-free approaches (DDA or DIA). Comprehensive data analysis is provided through a variety of database search engines and software packages. We also aid in bioinformatics analysis and generating publication-quality figures.

The Vector Core at the University of North Carolina at Chapel Hill (UNC Vector Core) operates as a full-service viral vector production organization. We have extensive experience in manufacturing of research grade vectors for academic, government, foundation, and biotech industry clients.

The UNCW-Crest Research Campus Spectroscopy Facility provides access to state-of-the-art NMR and MS instrumentation. Our core contains a 500- and 600-MHz NMR spectrometer along with multiple high- and low-resolution mass spectrometers. Access is preferentially given to UNCW students and staff with metered use provided for industrial partners.

The Metabolomics Facility houses a LECO GC-time of flight mass spectrometry and Agilent LC-time of flight mass spectrometry, which are suitable for small molecule metabolite profiling and high-throughput screening.

The mission of the Center for Marine Science at UNCW is to promote basic and applied research in the fields of oceanography, coastal and wetland studies, marine biomedical and environmental physiology, and marine biotechnology and aquaculture.

UNC-Chapel Hill hosts more than 50 core facilities. A wide range of services is provided from analytical chemistry to microscopy to X-ray crystallography among others. Access to services may vary. For more information download this brochure.

WFU is home to many core research facilities which include microscopy, X-ray, NMR, and computer facilities; biomechanics, human performance, blood chemistry, physical function and behavioral physiology laboratories; and a Center for Nanotechnology.