Shared Research Facilities and Equipment
Many facilities across North Carolina support life sciences research.
The listing covers core laboratory facilities at universities and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.
Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.
NCBiotech has funded equipment in many core facilities in the state.
NCBiotech's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing, please fill out this form.
The Duke Small Animal Irradiator Service Center facilities include a variety of different irradiator units which offers investigators several options for the irradiation of both cells and small animals. The available facilities are comprised of multiple orthovoltage cabinet irradiators, including the X-RAD 160, X-RAD 320, and the Xstrahl CIX3, which are suitable for both cell and small animal irradiation studies. We also have a high energy irradiator suitable for cell or whole animal irradiation. Finally, we have a micro-CT guided microirradiator, suitable for targeted, image-guided radiation therapy or for stand-alone micro-CT imaging (Xstrahl SARRP). Safety, quality assurance, and dosimetry are provided in collaboration with the Duke Radiation Safety Division.
Irradiator
Radiation therapy
CT Imaging
- Pharmaceutical & Drug Discovery
- Imaging & Microdissection
The Duke Magnetic Resonance Spectroscopy Center is a shared instrument facility. It provides access to high field NMR instrumentation, training and expert consultation on advanced applications for research at Duke and in the Southeastern region. 400, 2x500, 600, 2x700, and 800 MHz NMR spectrometers are available to users.
NMR spectroscopy, high field NMR, structural biology, molecular characterization
- Crystallography, X-ray Diffraction, NMR, & EPR
Our goal is to provide comprehensive and state of the art imaging for a wide-range of biological and other disciplines on and off the East Carolina University Campus for both research and teaching. Currently we can provide imaging in Conventional and Variable Pressure Scanning Electron Microscopy, Transmission Electron Microscopy, and Confocal Fluorescence Microscopy. We also have a range of basic bright-field, phase, differential interference contrast and fluorescence compound microscopes and basic stereo light microscopy.
SEM, X-ray Microanalysis, TEM, Confocal Microscopy, Brightfield and Fluorescence microscopy.
- Imaging & Microdissection
The facility houses both Inova 400 and 500 MHz spectrometers, as well as a 400MR spectrometer. The laboratory has experience and capabilities with both small molecule and natural product NMR, as well as biomolecular structure and dynamics.
NMR; small molecule NMR; natural-products NMR; biomolecular NMR; biomolecular structure and dynamics
- Crystallography, X-ray Diffraction, NMR, & EPR
- Other -omics & Analytical
This is an ISO/IEC 17025 certified lab, fully operationalized for ASTM, AATCC and ISO testing. Services include static testing at elevated and sub-ambient temperatures, dynamic and impact testing, conditioning, machining, metrology, strain gaging, research and quality control. A wide array of materials including composites, metals, plastics, ceramics, sandwich composites and core materials can be tested.
- Design Services & Machining
Gateway Research Park is a joint venture created by NC A&T State University and the University of North Carolina Greensboro to catalyze university research, innovation and economic development.
NanoBiology, Lab rental space
- Nanotechnology
The Share Resource serves Duke and non-Duke researchers with Illumina (Hiseq 2000/2500 and MiSeq), Ion Torrent (PGM and Proton), and PacBio sequencing.
Roche 454, Illumina, SOLiD
- Genetics & Genomics
The GSL provides Next Generation DNA sequencing, Sanger sequencing, genotyping and other support services to NC State faculty and the greater scientific research community.
Next Generation Sequencing (NGS) and Library Preparation using Illumina and PacBio platforms, Capillary DNA sequencing (Sanger) and Fragment analysis. Automated pipelines for nucleic extraction from tissues and high-throughput processing of samples using robotic liquid handling.
- Genetics & Genomics
The Genomics Core Facility provides DNA sequencing services for East Carolina University. The facility includes an Applied Biosystems 3130 Genetic Analyzer, Agilent 2100 Bioanalyzer, thermal cyclers, and Nanodrop 2000.
DNA and RNA quality analysis; nucleic acid sample preparation; DNA amplification; DNA sequencing; next-gen sequencing using the Ion Proton
- Genetics & Genomics
BTEC houses 63,000 GSF of fermentation, cell culture, recovery, purification, and analytical lab space for training NC State students and industry professionals in bioprocessing. BTEC also offers its space and expertise for protein production and purification, process/technology development, and analytical testing/development, serving both industry and other academic labs. Pre-clinical processing for non-human use only.
pre-clinical process development, analytical testing, analytical test development, cGMP training, fermentation, BL-2 laboratory, cell culture, centrifugation, homogenization, chromatography, ultrafiltration, diafiltration, filtration, clean utilities
- Bioprocessing
- Cell/Tissue Culture & Flow Cytometry
- Other -omics & Analytical
- Viral Vectors