Shared Research Facilities and Equipment

Many facilities across North Carolina support life science research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal.
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Region
Category
Facility Institution
Triangle
Durham
The Duke Magnetic Resonance Spectroscopy Center is a shared instrument facility. It provides access to high field NMR instrumentation, training and expert consultation on advanced applications for research at Duke and in the Southeastern region. 300, 400, 500, 600 and 800 MHz NMR spectrometers are available to users. Additional information and NMR Center policies can be found on the Center website https://sites.duke.edu/nmrcenter/instruments/
More information/services:

NMR spectroscopy, high field NMR, structural biology, molecular characterization

  • Crystallography, X-ray Diffraction, NMR, & EPR
Ronald Venters, PhD.
venters@duke.edu
(919) 613-8888
Triangle
Durham
The Duke Viral Vector Core (DVVC) provides services to investigators in custom design and construction, purification, and titering of various viral vector types for research use. Custom cloning includes assembly of viral vectors from simple one-step integration of genes into ready-to-go cassettes to multi-step cloning of complex constructs. DVVC has plasmids available that can produce short hairpin (sh) RNA for knocking down gene expression or bicistronic messages from IRES or P2A sequences. Viruses can be made so that protein expression (or knockdown) is constitutive or inducible. Constructs generated by the Core or provided by investigators serve as starting materials for generation of concentrated virus stocks. In addition, the Core has a number of ready-to-dispense aliquots of frequently used viral vectors (combining different reporters and effectors with a variety of promoters). The DVVC facilitates the use of these powerful research tools by investigators across diverse fields of study such as systems neuroscience, stem cell biology, metabolism, ageing, cancer biology and others. Services are open to researchers within the Duke University Medical Center, Duke University, as well as outside investigators.
More information/services:

molecular biology, cell culture, project design, virus production (lentivirus, retrovirus, g-deleted rabies virus, AAV)

  • Viral Vectors
Marguerita Klein
klein@neuro.duke.edu
(919) 684-0044
East
Greenville
Our goal is to provide comprehensive and state of the art imaging for a wide-range of biological and other disciplines on and off the East Carolina University Campus for both research and teaching. Currently we can provide imaging in Conventional and Variable Pressure Scanning Electron Microscopy, Transmission Electron Microscopy, and Confocal Fluorescence Microscopy. We also have a range of basic bright-field, phase, differential interference contrast and fluorescence compound microscopes and basic stereo light microscopy.
More information/services:

SEM, X-ray Microanalysis, TEM, Confocal Microscopy, Brightfield and Fluorescence microscopy.

  • Imaging & Microdissection
Tom Fink
finkt@ecu.edu
(252) 737-2300
Appalachian State University
West
Boone
The Enology Services Laboratory offers basic and advanced chemical analysis of craft beverage products. Detailed analyses such as phenolics, aroma compounds, and microbiology panels are also available. Call to discuss tailored analytical services.
More information/services:

Fermentation, wine, beer, grape, hop, phenolics, alcohol, distillate, food science, GC, HPLC, biofuels, sensory analysis

  • Other -omics & Analytical
Russell Kuhfeld
enology@appstate.edu
(828) 406-6014
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The facility houses both Inova 400 and 500 MHz spectrometers, as well as a 400MR spectrometer. The laboratory has experience and capabilities with both small molecule and natural product NMR, as well as biomolecular structure and dynamics.
More information/services:

NMR; small molecule NMR; natural-products NMR; biomolecular NMR; biomolecular structure and dynamics

  • Crystallography, X-ray Diffraction, NMR, & EPR
  • Other -omics & Analytical
Dr. Karl Koshlap
koshlap@unc.edu
(919) 962-0060
Gateway Research Park
Piedmont Triad
Greensboro
This is an ISO/IEC 17025 certified lab, fully operationalized for ASTM, AATCC and ISO testing. Services include static testing at elevated and sub-ambient temperatures, dynamic and impact testing, conditioning, machining, metrology, train gaging, nanoindentation, research and quality control. A wide array of materials including cmposites, metals, plastics, ceramics, sandwich composites and core materials can be tested.
  • Nanotechnology
  • Imaging & Microdissection
  • Design Services & Machining
Evan Kimbro
evank@gatewayurp.com
(336) 217-5184
Piedmont Triad
Greensboro
Gateway University Research Park ("Gateway") is a 501(c)3 not-for-profit entity created to manage and operate the joint collaboration between North Carolina A&T State University and The University of North Carolina at Greensboro for the purposes of supporting research and economic development within the Triad. Gateway is the bridge to successful commercial application of the research being performed at Greensboro’s two high research universities. The park’s flagship is the nation’s only Joint School of Nanoscience and Nanoengineering whose faculty, students and business partners will forge the products of the future. Gateway is developing two 75-acre campuses. The South campus is located on approximately 75 acres located off Lee Street near the I-40/85 interchange. The South Campus currently has one building comprising 63,000 square feet of space with another 105,000 square feet, which is the Joint School of Nanoscience and Nanoengineering, currently under construction.
More information/services:

Gateway University Research Park has state of the art research facilities for leading-edge work in the areas of life and physical sciences, engineering, technology and other applied sciences.

  • Nanotechnology
John Merrill
johnm@gatewayurp.com
(336) 375-9232
Triangle
Durham
The Share Resource serves Duke and non-Duke researchers with Illumina (Hiseq 2000/2500 and MiSeq), Ion Torrent (PGM and Proton), and PacBio sequencing.
More information/services:

Roche 454, Illumina, SOLiD

  • Genetics & Genomics
Oliver Fedrigo
sequencing@duke.edu
(919) 684-3359
North Carolina State University
Triangle
Raleigh
The GSL provides Next Generation DNA sequencing, Sanger sequencing, genotyping and other support services to NC State faculty and the greater scientific research community.
More information/services:

High-throughput sequencing using lllumina and LifeTech platforms, DNA sequencing (Sanger) and genotyping. Automated pipelines for nucleic extraction from tissues and high-throughput processing of samples using robotic liquid handling.

  • Genetics & Genomics
David Andrew Baltzegar, Ph.D.
dabaltze@ncsu.edu
(919) 513-0738
East Carolina University
East
Greenville
The Genomics Core Facility provides DNA sequencing services for East Carolina University. The facility includes an Applied Biosystems 3130 Genetic Analyzer, Agilent 2100 Bioanalyzer, thermal cyclers, and Nanodrop 2000.
More information/services:

DNA and RNA quality analysis; nucleic acid sample preparation; DNA amplification; DNA sequencing; next-gen sequencing using the Ion Proton

  • Genetics & Genomics
Denise Mayer
mayerd@ecu.edu
(252) 328-2607