Shared Research Facilities and Equipment

Many facilities across North Carolina support life sciences research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers or collaborators outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal. If you would like to submit a new listing or update an existing listing please fill this form.

 

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Region
Category
Facility Institution
North Carolina State University
Triangle
Raleigh

The AIF has numerous tools to support biological EM including a dedicated bio-TEM (Hitachi HT7800), Leica EM ICE high pressure freezer, Leica ACE900 Freeze fracture, three ultramicrotomes including a cryo ultramicrotome, a Leica cryostat and a Leica EM AFS2 freeze substitution unit.

More information/services:

High pressure freezing, freeze substitution, freeze fracture, cryo ultramicrotomy

  • Bioprocessing
Roberto Garcia
aif-contact@ncsu.edu
(919) 515-8628
Greater Charlotte
Kannapolis

The mission of the ASU Human Performance Laboratory is to investigate the influence of unique plant molecules on age-related loss of muscle mass (sarcopenia), muscle mitochondrial biogenesis, and exercise-induced immune dysfunction and oxidative stress.

More information/services:

Flavonoids, exercise testing, immune function

  • Human Performance, Nutrition, & Physiology
David C. Nieman, Dr. PH.
niemandc@appstate.edu
(828) 773-0056
University of North Carolina at Chapel Hill
Triangle
Chapel Hill

The Atomic Absorption Spectrometry Lab provides arsenic speciation analysis that determines the levels of inorganic arsenic and levels of its methylated metabolites in simple solutions and/or biological matrices.

More information/services:

Arsenic, Oxidation, Selenium, Speciation

Mirek Styblo, PhD
styblo@med.unc.edu
(919) 966-5721
North Carolina Central University
Triangle
Durham

This facility is to develop capability for drug efficacy and toxicity screen in accordance with Good Laboratory Practice (GLP) Regulations using the zebrafish model. Additional assays including behavioral and morphological assays in a high-throughput format will be used.

More information/services:

zebrafish, GLP studies, drug toxicity screen, behavioral assay, high throughput morphological assay

  • Imaging & Microdissection
  • Model Systems
  • Pharmaceutical & Drug Discovery
Derek Norford
dnorford@NCCU.EDU
(919) 530-7023
University of North Carolina at Charlotte
Greater Charlotte
Kannapolis

The Bioinformatics Services Division (BiSD) of UNC Charlotte provides a wide range of bioinformatics services to the North Carolina Research Campus (NCRC), UNC Charlotte and other life science companies throughout the country. Located on the NCRC in Kannapolis, North Carolina, our experienced team is adept at analyzing and interpreting the volumes of data produced by today's genomic technologies. Whether you are just considering a new project and need some advice or you already have a pile of data that you need to make sense of, we would be happy to talk with you.

More information/services:

Bioinformatics Analysis, Statistical Consultation, High Performance Computing, Custom data analysis, workflow development, Scripting support, Data Visualization, Data integration, Bioinformatics component of grant preparation.

  • Biostatistics, Bioinformatics, & HPC
Cory R. Brouwer, PhD
cbrouwer@charlotte.edu
(704) 687-8357
Biomolecular Characterization Facility
Duke University
Triangle
Durham

User-operated Aviv 62DS CD Spectropolarimeter with automated titrator, thermoelectric temperature control, simultaneous fluorescence and CD detection. Staff-operated Beckman XL-A analytical ultracentrifuge for sedimentation equilibrium and velocity. User fees apply.

More information/services:

circular dichroism, fluorescence, analytical ultracentrifugation, sedimentation velocity, sedimentation equilibrium, temperature control, automated titration

  • Other -omics & Analytical
Terrence G. Oas, Ph.D.
oas@duke.edu
(919) 684-4363
North Carolina State University
Triangle
Raleigh

The Biomolecular Interactions Core Facility (BICF) houses analytical equipment and resources for characterization of biomolecules and their interactions. Trainings are available on all instruments and we also accept submitted samples. We currently offer Isothermal Titration Calorimetry (ITC), Analytical Ultracentrifugation (AUC), Ultra Pressure Liquid Chromatography (UPLC), Circular Dichroism (CD), and Surface Plasmon Resonance (SPR).

More information/services:

AUC, Sedimentation Velocity, Sedimentation Equilibrium, ITC, CD, SPR, UPLC, ligand binding, protein-protein interactions, protein-DNA, protein-RNA, oligomerization, AAV analysis

  • Bioprocessing
  • Other -omics & Analytical
  • Pharmaceutical & Drug Discovery
Peter Thompson
pmthomps@ncsu.edu
(919) 515-0836
University of North Carolina at Chapel Hill
Triangle
Chapel Hill

The UNC Biomolecular NMR Laboratory (part of the UNC Center for Structural Biology) was created to support research into the structure and dynamics of biological molecules. The spectrometers are used to conduct studies of protein and nucleic acids in solution.

More information/services:

Bruker Avance III HD 850 Spectrometer, Bruker Avance III HD 700 MHz Spectrometer,Bruker Avance III HD 600 MHz Spectrometer,Bruker Avance III HD 500 MHz Spectrometer. Three TCI cryoprobes and one QCI. High-throughput Sample Jet sample changer,

  • Crystallography, X-ray Diffraction, NMR, & EPR
  • Bioprocessing
  • Nanotechnology
  • Other -omics & Analytical
  • Pathology/Histology
  • Pharmaceutical & Drug Discovery
Stu Parnham
stitch@ad.unc.edu
(919) 966-6184
University of North Carolina at Greensboro
Piedmont Triad
Greensboro

The BSBC provides high-performance computing resources to the scientific community (including faculty, scientists, and BioTech/BioPharma companies) in the Piedmont Triad area whose biotechnology research requires high-performance parallel computing. Application required (see http://bsbc.uncg.edu/).

More information/services:

Hardware: Dual load-sharing head nodes, 89 heterogeneous compute nodes, 752 CPU cores, 49,152 streaming GPU cores, 96 port Infiniband switch, 20-TB storage subsystem Software: NAMD, Conf Memories, NW Chem, AMBER

  • Biostatistics, Bioinformatics, & HPC
Patricia Reggio
bsbc_admin@uncg.edu
(336) 256-8610
North Carolina Community College System
West
Candler

The Natural Products Laboratory offers a variety of laboratory analytical and quality assurance testing services for life science businesses, researchers, educators and more. We also offer affordable rates for lab space and equipment rental.

More information/services:

Natural Products Laboratory, NPL, Herbal Medicine, Dietary Supplements, FDA, Herb, Herbal Good Manufacturing Practices, GMP, Herb School, Herbal GMP, Herbal GMP Manufacturing, Herbs, Food, Beverage, and Dietary Supplements

  • Bioprocessing
  • Other -omics & Analytical
npl@ncbionetwork.org
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