Development of a Pre-Clinical RNAi Chimeric Molecule for Treatment of Solid Tumors
NCBiotech Grants & Loans
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Organization
Enfuego Therapeutics, Inc.
Award Date
Award Amount
350,000
Program Name
Small Business Research Loan
Program Category
Business Financing
Principal Investigator
Michael Dombeck
Fiscal Year
2026
Region
Research Triangle
Project Description:
Enfuego Therapeutics of Morrisville received $350,00 to characterize and advance a chimeric RNAi molecule into IND-enabling work for future clinical development in the treatment of solid tumors. This molecule is unique in using RNAi to target mutant KRAS G12V and either MYC or panTEAD, to treat lung, pancreatic, and colorectal cancers