Applied Principles and Techniques of Depth Flow Filtration (DFF) and Tangential Flow Filtration (TFF) for BioPharm Downstream Purification Course

Join BTEC in partnership with John Rozembersky for this four-day comprehensive filtration
course. You will learn the fundamental principles and optimum applied techniques for
depth filtration (DFF) and tangential flow filtration (TFF) used today in biopharmaceutical
downstream purification.

The course begins with a one-day lecture that is designed to help individuals gain a
solid understanding of the parameters and factors that affect DFF and TFF membrane
performance and product recovery for both cell clarification and UF/DF biopharmaceutical applications. Depth filtration (DFF) covers polymeric membrane and matrix media
technologies and tangential flow filtration (TFF) covers both flat sheet cassette and
hollow fiber element configurations.

The three-day hands-on laboratory workshop that follows enables you to perform
DFF and TFF application trials using state-of-the-art benchtop systems. Two full-day
sessions are dedicated to cell clarification with DFF on day one and TFF on day two.
Day three focuses on UF/DF by TFF. Data developed during these trials will be applied to
a real scale-up system problem and SOP. The principles and techniques presented in the
day-one lecture are applied in this workshop, which is limited to 12 participants.