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Development of Ladder Frame Polyethers as Drug Escortins

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Award date: 
Oct 25, 2011
Award amount: 
Organization name: 
UNC - Wilmington
Principal Investigator: 
Bourdelais, Andrea J.
Grant program category: 
Research and Equipment Support
Grant program name: 
Multidisciplinary Research Grant

A major hurdle in the development of new therapeutic drugs is getting them inside cells and to their site of action. This proposal aims to develop natural ladder frame polyethers and small synthetic ladder frame polyethers as drug carriers to improve the cellular uptake of drugs with low membrane permeability.

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