Shared Research Facilities and Equipment

Many facilities across North Carolina support life science research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal.
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Region
Category
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The CGIBD's Advanced Analytics (AA) Core provides high-quality, quantitative solutions for studying proteins, peptides, and other molecules, including mRNA and cDNA. The Core's immunotechnologies (IT) component provides consultation, ordering, and immunoassay services, and supports a wide variety of analytes in both traditional ELISA/EIA and xMAP-based multiplex bead assay formats. The AA Core also offers high-throughput real-time qPCR service on its Fluidigm BioMark HD system, allowing users to simultaneously measure as many as 96 samples for up to 96 genes, and requiring as little as a single cell per sample when used in combination with the Core's C1 single-cell auto prep system.
More information/services:

Fluidigm, C1, BioMark, Luminex, ELISA, multiplex, immunoassay, qPCR, gene expression, RNAseq, miRNA expression, single cell, DNA sequencing, genome sequencing, SNP genotyping, Olink, high throughput, protein analysis

  • Genetics & Genomics
  • Immunology/Antibody Production
  • Other -omics & Analytical
Carlton Anderson
canderson@med.unc.edu
(919) 260-3461
North Carolina State University
Triangle
Raleigh
The Analytical Instrumentation Facility (AIF) is NC State’s core facility for electron microscopy, spectroscopy, and nanomaterials characterization. The AIF supports state-of-the-art scanning and transmission electron microscopy (SEM and TEM), X-ray scattering and spectroscopy, mass spectrometry, scanning probe and Raman microscopy, nanoindentation, and hosts extensive sample preparation facilities. The AIF has tools to support biological EM including cryo-SEM, cryo-TEM, and cryomicrotome.
More information/services:

electron microscopy, spectroscopy, spectrometry, diffraction, atomic force microscopy, nanoindentation

  • Nanotechnology
  • Imaging & Microdissection
  • Diagnostic Microbiology
  • Crystallography, X-ray Diffraction, NMR, & EPR
Roberto Garcia
aif-contact@ncsu.edu
(919) 515-8628
Greater Charlotte
Kannapolis
The mission of the ASU Human Performance Laboratory is to investigate the influence of unique plant molecules on age-related loss of muscle mass (sarcopenia), muscle mitochondrial biogenesis, and exercise-induced immune dysfunction and oxidative stress.
More information/services:

Flavonoids, exercise testing, immune function

  • Human Performance, Nutrition, & Physiology
David C. Nieman, Dr. PH.
niemandc@appstate.edu
(828) 773-0056
North Carolina Central University
Triangle
Durham
This facility is to develop capability for drug efficacy and toxicity screen in accordance with Good Laboratory Practice (GLP) Regulations using the zebrafish model. Additional assays including behavioral and morphological assays in a high-throughput format will be used.
More information/services:

zebrafish, GLP studies, drug toxicity screen, behavioral assay, high throughput morphological assay

  • Imaging & Microdissection
  • Model Systems
  • Pharmaceutical & Drug Discovery
Derek Norford
dnorford@NCCU.EDU
(919) 530-7023
Triangle
Durham
The Biofluid Shared Resource facility uses state-of-the-art automation for the extraction and allocation of DNA. Extensive quality-control ensures maximum investigator confidence in sample processing and storage.
More information/services:

DNA extraction, RNA, blood, tissue, liquid handling, clinical, Oragene, storage, sample tracking, Biobank, licensable samples

  • Biorepository
  • Genetics & Genomics
David Layfield
david.layfield@duke.edu
(919) 668-0232
University of North Carolina at Charlotte
Greater Charlotte
Kannapolis
The Bioinformatics Services Division (BiSD) of UNC Charlotte provides a wide range of bioinformatics services to the North Carolina Research Campus (NCRC), UNC Charlotte and other life science companies throughout the country. Located on the NCRC in Kannapolis, North Carolina, our experienced team is adept at analyzing and interpreting the volumes of data produced by today's genomic technologies. Whether you are just considering a new project and need some advice or you already have a pile of data that you need to make sense of, we would be happy to talk with you.
More information/services:

Bioinformatics Analysis, Statistical Consultation, High Performance Computing, Custom data analysis, workflow development, Scripting support, Data Visualization, Data integration, Bioinformatics component of grant preparation.

  • Biostatistics, Bioinformatics, & HPC
Cory R. Brouwer, PhD
Cory.Brouwer@uncc.edu
(704) 687-8357
Triangle
Durham
User-operated Aviv 62DS CD Spectropolarimeter with automated titrator, thermoelectric temperature control, simultaneous fluorescence and CD detection. Staff-operated Beckman XL-A analytical ultracentrifuge for sedimentation equilibrium and velocity. User fees apply.
More information/services:

circular dichroism, fluorescence, analytical ultracentrifugation, sedimentation velocity, sedimentation equilibrium, temperature control, automated titration

  • Other -omics & Analytical
Terrence G. Oas, Ph.D.
oas@duke.edu
(919) 684-4363
University of North Carolina at Greensboro
Piedmont Triad
Greensboro
The BSBC provides high-performance computing resources to the scientific community (including faculty, scientists, and BioTech/BioPharma companies) in the Piedmont Triad area whose biotechnology research requires high-performance parallel computing. Application required (see http://bsbc.uncg.edu/).
More information/services:

Hardware: Dual load-sharing head nodes, 89 heterogeneous compute nodes, 752 CPU cores, 49,152 streaming GPU cores, 96 port Infiniband switch, 20-TB storage subsystem Software: NAMD, Conf Memories, NW Chem, AMBER

  • Biostatistics, Bioinformatics, & HPC
Patricia Reggio
bsbc_admin@uncg.edu
(336) 256-8610
University of North Carolina at Pembroke
Southeast
Pembroke
Fermentation: bench to pilot scale We will provide affordable, practical hands-on training on bioreactor set-up, operation and harvest. Also, we will grow biomass (non-cGMP) for customers.
More information/services:

fermentation technology; microbial liquid culture

  • Bioprocessing
Len Holmes
len.holmes@uncp.edu
(910) 521-6650
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The BRIC Small Animal Imaging facility provides imaging of small species, including mice, rats, etc., as well as in vitro specimens. On-site modalities include MRI, optical, CT, PET, SPECT and ultrasound. With expertise in study design, animal models, image acquisition and image analysis, the Small Animal Imaging facility helps investigators from grant application to publication. Services are available to investigators from all academic and industry labs.
More information/services:

imaging, small animal imaging, MRI, PET, microPET, SPECT, nuclear medicine, CT, microCT, ultrasound, US, optical, fluorescence, luminescence, autoradiography, DXA, DEXA, image analysis

  • Imaging & Microdissection
Hong Yuan, PhD
bricsai@unc.edu
(919) 843-3813