Shared Research Facilities and Equipment

Many facilities across North Carolina support life science research.

The listing covers core laboratory facilities at university and nonprofit research institutions that are open to researchers outside of their home institutions.

Representatives of the core facilities listed below have voluntarily submitted their information. Not all institutions list available core lab facilities, but many are in the process of organizing and compiling these resources. As this information becomes available, we'll add those links.

NCBiotech has funded equipment in many core facilities in the state.

The Center's ongoing role is to provide this information portal.
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Region
Category
Facility Institution
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The CGIBD’s Advanced Analytics (AA) Core provides high-quality, quantitative solutions for studying proteins and nucleic acids at the bulk or single-cell level. The Core offers a wide variety of services, including: single cell genomics (10x Genomics and Fluidigm C1), single cell protein detection (Protein Simple Milo), high-throughput PCR/qPCR (Fluidigm BioMark HD), immunoassays (ELISA/EIA/multiplex), cell sorting (FACS), and Illumina sequencing (NextSeq 500).
More information/services:

10x Genomics, Fluidigm, C1, BioMark, Luminex, ELISA, multiplex, immunoassay, qPCR, gene expression, RNA-seq, ATAC-seq, REAP-seq, miRNA expression, single cell, DNA-seq, sequencing, SNP genotyping, CNV, high throughput, protein analysis

  • Genetics & Genomics
  • Immunology/Antibody Production
  • Other -omics & Analytical
Carlton Anderson
canderson@med.unc.edu
(919) 260-3461
North Carolina State University
Triangle
Raleigh
The Analytical Instrumentation Facility (AIF) is NC State’s core facility for electron microscopy, spectroscopy, and nanomaterials characterization. The AIF supports state-of-the-art scanning and transmission electron microscopy (SEM and TEM), X-ray scattering and spectroscopy, mass spectrometry, scanning probe and Raman microscopy, nanoindentation, and hosts extensive sample preparation facilities. The AIF has tools to support biological EM including cryo-SEM, cryo-TEM, and cryomicrotome.
More information/services:

electron microscopy, spectroscopy, spectrometry, diffraction, atomic force microscopy, nanoindentation

  • Crystallography, X-ray Diffraction, NMR, & EPR
  • Diagnostic Microbiology
  • Imaging & Microdissection
  • Nanotechnology
Roberto Garcia
aif-contact@ncsu.edu
(919) 515-8628
Greater Charlotte
Kannapolis
The mission of the ASU Human Performance Laboratory is to investigate the influence of unique plant molecules on age-related loss of muscle mass (sarcopenia), muscle mitochondrial biogenesis, and exercise-induced immune dysfunction and oxidative stress.
More information/services:

Flavonoids, exercise testing, immune function

  • Human Performance, Nutrition, & Physiology
David C. Nieman, Dr. PH.
niemandc@appstate.edu
(828) 773-0056
North Carolina Central University
Triangle
Durham
This facility is to develop capability for drug efficacy and toxicity screen in accordance with Good Laboratory Practice (GLP) Regulations using the zebrafish model. Additional assays including behavioral and morphological assays in a high-throughput format will be used.
More information/services:

zebrafish, GLP studies, drug toxicity screen, behavioral assay, high throughput morphological assay

  • Imaging & Microdissection
  • Model Systems
  • Pharmaceutical & Drug Discovery
Derek Norford
dnorford@NCCU.EDU
(919) 530-7023
Triangle
Durham
The Biofluid Shared Resource facility uses state-of-the-art automation for the extraction and allocation of DNA. Extensive quality-control ensures maximum investigator confidence in sample processing and storage.
More information/services:

DNA extraction, RNA, blood, tissue, liquid handling, clinical, Oragene, storage, sample tracking, Biobank, licensable samples

  • Biorepository
  • Genetics & Genomics
David Layfield
david.layfield@duke.edu
(919) 668-0232
University of North Carolina at Charlotte
Greater Charlotte
Kannapolis
The Bioinformatics Services Division (BiSD) of UNC Charlotte provides a wide range of bioinformatics services to the North Carolina Research Campus (NCRC), UNC Charlotte and other life science companies throughout the country. Located on the NCRC in Kannapolis, North Carolina, our experienced team is adept at analyzing and interpreting the volumes of data produced by today's genomic technologies. Whether you are just considering a new project and need some advice or you already have a pile of data that you need to make sense of, we would be happy to talk with you.
More information/services:

Bioinformatics Analysis, Statistical Consultation, High Performance Computing, Custom data analysis, workflow development, Scripting support, Data Visualization, Data integration, Bioinformatics component of grant preparation.

  • Biostatistics, Bioinformatics, & HPC
Cory R. Brouwer, PhD
Cory.Brouwer@uncc.edu
(704) 687-8357
Triangle
Durham
User-operated Aviv 62DS CD Spectropolarimeter with automated titrator, thermoelectric temperature control, simultaneous fluorescence and CD detection. Staff-operated Beckman XL-A analytical ultracentrifuge for sedimentation equilibrium and velocity. User fees apply.
More information/services:

circular dichroism, fluorescence, analytical ultracentrifugation, sedimentation velocity, sedimentation equilibrium, temperature control, automated titration

  • Other -omics & Analytical
Terrence G. Oas, Ph.D.
oas@duke.edu
(919) 684-4363
University of North Carolina at Chapel Hill
Triangle
Chapel Hill
The UNC Biomolecular NMR Laboratory (part of the UNC Center for Structural Biology) was created to support research into the structure and dynamics of biological molecules. The spectrometers are used to conduct studies of protein and nucleic acids in solution.
More information/services:

Bruker Avance III HD 850 Spectrometer, Bruker Avance III HD 700 MHz Spectrometer,Bruker Avance III HD 600 MHz Spectrometer,Bruker Avance III HD 500 MHz Spectrometer. Three TCI cryoprobes and one QCI. High-throughput Sample Jet sample changer,

  • Crystallography, X-ray Diffraction, NMR, & EPR
  • Bioprocessing
  • Nanotechnology
  • Other -omics & Analytical
  • Pathology/Histology
  • Pharmaceutical & Drug Discovery
Stu Parnham
stitch@ad.unc.edu
(919) 966-6184
University of North Carolina at Greensboro
Piedmont Triad
Greensboro
The BSBC provides high-performance computing resources to the scientific community (including faculty, scientists, and BioTech/BioPharma companies) in the Piedmont Triad area whose biotechnology research requires high-performance parallel computing. Application required (see http://bsbc.uncg.edu/).
More information/services:

Hardware: Dual load-sharing head nodes, 89 heterogeneous compute nodes, 752 CPU cores, 49,152 streaming GPU cores, 96 port Infiniband switch, 20-TB storage subsystem Software: NAMD, Conf Memories, NW Chem, AMBER

  • Biostatistics, Bioinformatics, & HPC
Patricia Reggio
bsbc_admin@uncg.edu
(336) 256-8610
University of North Carolina at Pembroke
Southeast
Pembroke
Fermentation: bench to pilot scale We will provide affordable, practical hands-on training on bioreactor set-up, operation and harvest. Also, we will grow biomass (non-cGMP) for customers.
More information/services:

fermentation technology; microbial liquid culture

  • Bioprocessing
Len Holmes
len.holmes@uncp.edu
(910) 521-6650