Developing Small Molecule Inhibitors of CIB1
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Organization
UNC - Chapel Hill
Award Date
Award Amount
100,000
Program Name
Biotechnology Innovation Grant
Program Category
Research and Equipment Support
Principal Investigator
Leslie Parise
Fiscal Year
2017
Region
Research Triangle
Project Description:
Triple negative breast cancer (TNBC) is an extremely challenging type of cancer to treat successfully and currently has few therapeutic options. Triple negative cancers are more difficult to treat because they lack the three receptors on their cell surface that hormonal drugs attacks. CIB1 is a protein that appears to promote TNBC cell survival. Here we propose to develop a drug that inhibits CIB1, for the treatment of TNBC.