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Treatment of Dopamine Agonist-induced Augmentation with a D1 Receptor Blocker in Patients with Restless Legs Syndrome (RLS)

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Award date: 
Jun 7, 2016
Award amount: 
Organization name: 
East Carolina University
Principal Investigator: 
Clemens, Stefan
Grant program category: 
Research and Equipment Support
Grant program name: 
Biotechnology Innovation Grant

Restless Leg Syndrome (RLS) is a life-long neurological disorder that affects an estimated 10-20 million Americans. Treatment for RLS is centered on dopamine drugs that are initially effective, but over time lose their efficacy. We propose clinical testing of a new therapy that will overcome this loss of efficacy.

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