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Proof of MOA - Projects for HIV and Staph Aureus tRNA Inhibitors

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Award date: 
Jun 29, 2012
Award amount: 
Organization name: 
Trana Discovery, Inc.
Principal Investigator: 
Peterson, Steven E.
Grant program category: 
Business Financing
Grant program name: 
Small Business Research Loan
Research Triangle

Projects will illustrate the proposed mechanism of action for bioactive hits active against HIV and Staph aureus are essential and unique among anti-infective therapies. The NMR results will confirm and allow identification for future combinatorial chemisty work and for S. aureus, the footprinting will confirm where the bioactive hits impact the ribosome.

Fiscal year: