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Preliminary Safety Screening of Duke LpxC Inhibitors as Novel Antibiotics Against Gram-Negative Bacteria

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Award date: 
Oct 7, 2015
Award amount: 
Organization name: 
Duke University Medical Center
Principal Investigator: 
Thomas, Dennis
Grant program category: 
Research and Equipment Support
Grant program name: 
Technology Enhancement Grant
Research Triangle

Multi-drug resistant bacterial infection is a widespread and serious public health threat that demands the commercial development of novel antibiotics. This proposal aims to evaluate the safety profile of novel antibiotics discovered at Duke University in order to establish their suitability for further development into clinical therapies.

Fiscal year: