Identification and Validation of Novel Therapies for the Inhibition of Atherosclerotic Plaque Lesions
Atherosclerosis is a chronic inflammatory disease affecting millions of Americans. Treatment of the disease is extremely expensive and contributes to the rising cost of healthcare. The PIs have discovered a potential clinically important way to prevent heart attack and stroke due to atherosclerosis. This new discovery has important implications for the development of new ways to treat this disease as it represents a novel way to prevent the disease that differs from commercially available therapies (e.g. statins). This discovery could lead to paradigm-shifting strategies for preventing one of the most costly and debilitating diseases in humans.