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Development of Novel Peptides to Treat Diseases of Na+ Absorption (Resubmission)

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Award date: 
Jun 4, 2013
Award amount: 
$300,000
Organization name: 
UNC - Chapel Hill
Principal Investigator: 
Tarran, Robert
Grant program category: 
Research and Equipment Support
Grant program name: 
Multidisciplinary Research Grant
Region: 
Research Triangle

Cystic fibrosis mucus is dehydrated due to a genetically induced imbalance in salt and water transport leaving the lungs prone to mucus plugging and infections. We propose to develop novel peptides that can inhibit excessive salt absorption in CF airways to improve CF mucus hydration and prevent infection.

Fiscal year: 
2013