Grant Funding Opportunities: 5/16/2014
Weekly Grant Funding Opportunities
Please feel free to send special funding search requests any time (susan_craft@ncbiotech.org). Grant funding requests are included our regular research and include a fee of $100/hour. Also, let us know if any of your partners have submitted grant applications to funding announcements posted in the weekly grant alert emails. We would love to hear of their successes!
Visit NCBiotech’s Funding Gateway page to get more information on funding announcements, links to opportunity search databases and grant development tips.
Announcements
NCET2 is offering an online workshop on Applying to the NIH SBIR Phase I Program for First-Time Applicants – a practical step-by-step, four-hour online "How-To" workshop over two evenings to help researchers, faculty members, graduate students, post-docs and entrepreneurs create a SBIR company and apply to the NIH SBIR program in August of 2014. Taught by former NIH SBIR directors, this workshop includes a post-course review of the applicant's proposed SBIR application by our experts before submission to the NIH.
Upcoming Deadlines
Deadline: 6/1/2014
Agency: Food & Drug Administration
Program: Development of realistic in vitro studies to assess robustness of dose counters/indicators in metered dose inhalers (U01)
Description: Metered dose inhalers (MDIs) consist of a formulation, with active ingredient(s) and possibly excipients in a propellant contained in a pressurized canister, and are aerosolized using a valve fitted to an actuator. Dose counters/indicators are an add-on mechanism to MDIs and aid in tracking the number of doses remaining in the canister. According to the Guidance for Industry: Integration of Dose-Counting Mechanisms into MDI Drug Products (March 2003), in vitro testing (simulating both actual-use and misuse) and in-use studies are recommended to be conducted in order to establish functionality, reliability, and accuracy of dose counters/indicators in MDIs. The in-use studies supplement the in vitro testing and provide information regarding any problems when the dose counter/indicator is used in a clinical setting. The potential failure modes reported for MDI dose counters/indicators include, but are not limited to, undercounting, over counting and count(s) upon dropping.In general, in vitro robustness studies for MDIs include, but are not limited to, effect of dropping, shaking, exposure to temperature extremes, shipping, and storage under accelerated conditions on MDI drug product performance. Due to limited information available on the relevance of these in vitro robustness studies to clinical outcomes, it may be difficult to predict the failure modes of dose counters/indicators in MDIs under actual-use conditions. Therefore, there is a need to develop new or improve the existing in vitro studies used to assess robustness of dose counters/indicators in MDIs to better predict occurrence and type of failure for dose counters/indicators under actual-use conditions.The goal of this study is to develop clinically relevant in vitro studies to assess robustness of dose counters/indicators in MDIs representing the actual-use/misuse conditions. This study will consist of three phases. Phase 1: Select two commercially available MDIs with dose counters/indicators. Phase 2: Design new or modify existing in vitro methods and conduct in vitro robustness studies for the MDIs selected in Phase 1. Identify the intensity of in vitro tests needed to cause product failures, while ensuring that the proposed tests are predictive and relevant to actual-use conditions. Phase 3: Validate the proposed in vitro robustness studies using other marketed MDIs with dose counters/indicators.
Award Amount: $500,000
Website: www.grants.nih.gov/grants/guide/rfa-files/RFA-FD-14-025.html
Eligibility: State, county or city governments; public and private institutes of higher education; school districts; small businesses; nonprofits; Native American tribal organizations; others
Deadline: 5/19/2014 (LOI); 6/19/2014 (application)
Agency: National Institutes of Health
Program: Development of Software and Analysis Methods for Biomedical Big Data in Targeted Areas of High Need (U01)
Description: In response to the spectacular opportunities and immense challenges presented by the dawning era of "Big Data" in biomedical research, NIH has developed the Big Data to Knowledge (BD2K) initiative with the mission of enabling the biomedical research community to use the various types of Big Data for research. The purpose of this Funding Opportunity Announcement (FOA) is to solicit development of analysis methods and software in the four topic areas of data compression/reduction, data visualization, data provenance, and data wrangling as part of the overall BD2K initiative.
Award Amount: $300,000
Website: http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-14-020.html
Eligibility: State, county or city governments; public and private institutes of higher education; school districts; small businesses; nonprofits; Native American tribal organizations; others
New Opportunities
Deadline: 6/10/2014
Agency: National Science Foundation
Program: Small Business Innovation Research Program
Description: The Small business Innovation Research (SBIR) Program stimulates technological innovation in the private sector by strengthening the role of small business concerns in meeting Federal research and development needs, increasing the commercial application of federally supported research results, and fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses. The SBIR program solicits proposals from the small business sector consistent with NSF's mission. The program is governed by Public Law 112-81 (SBIR/STTR Reauthorization Act of 2011). A main purpose of the legislation is to stimulate technological innovation and increase private sector commercialization. The NSF SBIR program is therefore in a unique position to meet both the goals of NSF and the purpose of the SBIR legislation by transforming scientific discovery into both social and economic benefit, and by emphasizing private sector commercialization. Accordingly, NSF has formulated broad solicitation topics for SBIR that conform to the high-technology investment sector's interests. The topics are detailed on the SBIR/STTR topics homepage.
Award Amount: Varies
Website: http://www.nsf.gov/pubs/2014/nsf14539/nsf14539.htm
Eligibility: Only firms qualifying as a small business concern are eligible to participate
Deadline: 6/11/2014
Agency: National Science Foundation
Program: Small Business Technology Transfer Program
Description: The Small Business Technology Transfer (STTR) Program stimulates technological innovation in the private sector by strengthening the role of small business concerns in meeting Federal research and development needs, increasing the commercial application of federally supported research results, and fostering and encouraging participation by socially and economically disadvantaged and women-owned small businesses. The STTR program solicits proposals from the small business sector consistent with NSF's mission. The program is governed by Public Law 112-81 (SBIR/STTR Reauthorization Act of 2011). A main purpose of the legislation is to stimulate technological innovation and increase private sector commercialization. The NSF STTR program is therefore in a unique position to meet both the goals of NSF and the purpose of the SBIR/STTR legislation by transforming scientific discovery into both social and economic benefit, and by emphasizing private sector commercialization. The STTR Program requires researchers at universities, Federally-Funded Research and Development Centers (FFRDCs), and other non-profit research institutions to play a significant intellectual role in the conduct of each STTR project. These researchers, by joining forces with a small company, can spin-off their commercially promising ideas while they remain primarily employed at the research institution. This STTR Phase I solicitation aims at encouraging the commercialization of previously NSF-funded fundamental research (NSF funding lineage). It is highly desirable that the core innovation described in the submitted proposals can in some manner be linked to fundamental research funded by the NSF. This lineage must be documented in the Project Description section of the proposal here).
Award Amount: Varies
Website:www.nsf.gov/funding/pgm_summ.jsp?pims_id=505028&WT.mc_id=USNSF_44&WT.mc_ev=click
Eligibility: Only firms qualifying as a small business concern are eligible to participate
Deadline: 6/11/2014
Agency: Food and Drug Administration
Program: Pharmacokinetic/Pharmacodynamic (PK/PD) Studies of Methylphenidate Extended Release Products in Attention Deficit Hyperactivity Disorder (ADHD) Patients
Description: The purpose of this project is to conduct a prospective PK/PD study in attention deficit hyperactivity disorder (ADHD) patients to link the PK profiles to the time-course of PD activity of methylphenidate extended release products in order to identify additional PK metrics (if any) that may impact the therapeutic equivalence of methylphenidate extended release products. The findings from the PK/PD study will help establish scientific and regulatory standards for assuring therapeutic equivalence of generic methylphenidate extended release products.
Award Amount: $1,000,000.00
Website: www.grants.gov/web/grants/view-opportunity.html?oppId=254474
Eligibility: State, county or city governments; public and private institutes of higher education; school districts; small businesses; nonprofits; Native American tribal organizations; others
Deadline: 7/24/2014
Agency: National Institutes of Health
Program: Chronic Wounds: Advancing the Science from Prevention to Healing
Description: This Funding Opportunity Announcement (FOA) seeks to stimulate research that will increase the understanding of biological and psychosocial factors associated with development, progression, and repair of chronic wounds (e.g., diabetic ulcers, pressure ulcers, venous and arterial ulcers) and associated adverse outcomes, and to develop and test interventions aimed at preventing the onset of chronic wounds, expediting the healing process, or alleviating wound-related symptoms. It is anticipated that the findings from this research will expand the body of knowledge needed to identify individuals at the highest risk for developing chronic wounds and to inform the search for tailored treatments to improve outcomes and quality of life for millions of persons at risk for or suffering from chronic wounds.
Award Amount: $ 350,000
Website: www.grants.gov/web/grants/view-opportunity.html?oppId=254782
Eligibility: State, county or city governments; public and private institutes of higher education; school districts; small businesses; nonprofits; Native American tribal organizations; others
Deadline: 7/30/2014
Agency: Department of Defense
Program: DoD Peer Reviewed Medical Discovery Award
Description: The intent of the PRMRP Discovery Award is to support innovative, untested, high-risk/ potentially high-reward research that will provide new insights, paradigms, technologies, or applications. Studies supported by this award are expected to lay the groundwork for future avenues of scientific investigation. The proposed research project should include a well-formulated, testable hypothesis based on a sound scientific rationale and study design. The proposed research project should be novel and innovative. Innovative research may introduce a new paradigm, challenge existing paradigms, look at existing problems from new perspectives, or exhibit other highly creative qualities. Research that is an incremental advance upon published data is not considered innovative and is not consistent with the intent of this award mechanism. Inclusion of preliminary data is strongly discouraged. The outcome of research supported by this award should be the generation of robust preliminary data that can be used as a foundation for future research projects to understand the mechanisms of initiation or progression and/or improving patient care for a disease or condition. The Discovery Award is not intended to support a logical progression of an already established research project or other types of ongoing work; therefore, inclusion of preliminary data other than serendipitous findings or in small amounts is not consistent with the exploratory nature of this award. The presentation of substantial preliminary data suggests that the proposed research project would be more appropriately submitted to a different award mechanism.
Award Amount: $ 12,000,000
Website: www.grants.gov/web/grants/view-opportunity.html?oppId=254515
Eligibility: Unrestricted